Evidence supporting the use of: Kigelia africana
For the health condition: Ulcerations (external)

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Kigelia africana, commonly known as the sausage tree, has a long history of use in African traditional medicine for treating various skin ailments, including external ulcerations, wounds, and sores. Ethnobotanical surveys and reports from several African countries document the application of Kigelia africana fruit extracts or topical preparations to promote healing of ulcers and lesions. The traditional rationale is based on observed wound-healing and antimicrobial properties. Some preliminary laboratory studies provide partial scientific backing for these traditional uses. Certain extracts of Kigelia africana have demonstrated antibacterial and antifungal activity in vitro, as well as modest wound-healing effects in animal models. However, robust clinical trials in humans are lacking, and the available in vivo data are limited and not conclusive. The mechanisms proposed in preclinical studies include the presence of iridoids, naphthoquinones, and flavonoids, which may contribute to antimicrobial and anti-inflammatory actions. In summary, while there is a well-documented traditional use of Kigelia africana for external ulcerations, and some preliminary lab and animal evidence for its antimicrobial and healing properties, the scientific validation is currently insufficient. Further rigorous clinical research is required to establish its efficacy and safety for treating external ulcerations in humans.

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