Evidence supporting the use of: Paeonia moutan
For the health condition: Ulcerations (external)

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Paeonia moutan, also known as moutan peony or "Mu Dan Pi" in Traditional Chinese Medicine (TCM), has a historical use in the treatment of external ulcerations, wounds, and skin infections. Classical TCM texts, including the "Shennong Bencao Jing" and later materia medica compendia, document the use of Paeonia moutan root bark as a topical application for sores, carbuncles, and ulcerated skin. Its traditional use is based on the belief that it "clears heat," "cools the blood," and disperses stasis, which in TCM theory is associated with the formation of ulcers and skin lesions.

Modern pharmacological studies have identified several bioactive compounds in Paeonia moutan, such as paeonol and paeonoside, which exhibit anti-inflammatory and antimicrobial activities [1]. However, direct clinical evidence for efficacy in external ulcerations is limited, and most studies are preclinical or in vitro. While these properties provide a plausible rationale for its traditional use, robust clinical trials in humans are lacking. Therefore, the justification for using Paeonia moutan externally for ulcerations is rooted primarily in traditional medicine, with partial support from laboratory research but insufficient high-quality clinical evidence.

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