Evidence supporting the use of: Sangre de Grado
For the health condition: Ulcerations (external)

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Synopsis

Source of validity: Traditional
Rating (out of 5): 3

Sangre de Grado (also known as Dragon’s Blood, derived from the sap of the Croton lechleri tree) has a long history of traditional use in South American herbal medicine for treating external ulcerations and wounds. Indigenous peoples of the Amazon have applied the sap directly to skin ulcers, cuts, and sores for centuries, valuing its ability to form a protective layer, reduce inflammation, and promote healing. This traditional application is supported by the sap’s high content of proanthocyanidins (antioxidant compounds), which are thought to contribute to its astringent and antimicrobial properties.

Some modern studies have investigated in vitro and animal models, showing that Sangre de Grado may inhibit bacterial growth and accelerate wound healing, and a few small clinical studies have indicated benefits in healing ulcers and skin lesions. However, robust, large-scale human clinical trials are limited, and most of the evidence for its efficacy in treating external ulcerations remains rooted in traditional use and preliminary pharmacological studies rather than definitive scientific validation. Nevertheless, the convergence of longstanding traditional practices and emerging, albeit limited, scientific data supports its ongoing use for this purpose in some herbal and complementary medicine contexts.

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