Evidence supporting the use of: Silver (usp)
For the health condition: Ulcerations (external)

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Silver, particularly in the form of silver sulfadiazine or silver-impregnated dressings, has a scientifically validated role in the management of external ulcerations, such as chronic wounds, burns, and pressure ulcers. Silver’s antimicrobial properties have been recognized for centuries, but its clinical application in modern wound care is supported by research demonstrating its ability to reduce bacterial load and prevent infection in ulcerated tissue. Randomized controlled trials and systematic reviews have found that silver-containing dressings may decrease wound bioburden and promote healing in certain situations, especially in ulcers at high risk of infection or those with delayed healing due to microbial colonization.

However, the overall quality of evidence varies, and some reviews (e.g., Cochrane) note that while silver dressings can reduce infection rates, their impact on actual wound healing time is less clear. Furthermore, long-term use can potentially lead to local tissue toxicity or delayed wound healing, and routine use on non-infected wounds is not universally recommended. In summary, the use of silver for external ulcerations is supported by scientific studies, particularly for infection control, though its effect on wound healing per se is less robustly established and should be considered on a case-by-case basis.

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Products containing Silver (usp)

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