There is some emerging scientific evidence supporting the use of arugula (Eruca sativa) for the management of ulcers, particularly gastric ulcers. Preclinical studies have shown that extracts from arugula leaves and seeds possess gastroprotective properties in animal models. For example, research published in Phytotherapy Research (2009) and other journals has demonstrated that arugula extract can reduce the formation and severity of gastric lesions induced by chemicals such as ethanol or indomethacin in rats. The proposed mechanisms include antioxidant effects, enhancement of gastric mucus production, and reduction of gastric acid secretion, as well as anti-inflammatory activities.

However, it is important to note that most of the evidence comes from laboratory and animal studies; there are currently no robust clinical trials in humans confirming arugula's efficacy for treating or preventing ulcers. Traditionally, arugula has been used as a digestive aid in some cultures, but its specific use for ulcers is not widely documented in herbal medicine literature. Therefore, while there is a scientific rationale and some positive preclinical findings, the overall level of evidence is still limited and preliminary.

In summary, arugula shows promise as a supportive agent for ulcers based on animal studies, but more research, particularly in humans, is needed to confirm its efficacy and safety for this condition.