Relationship: Ulcers and grape

Evidence supporting the use of: Grape
For the health condition: Ulcers

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Grape, particularly grape seeds and skins, contains a variety of polyphenolic compounds such as resveratrol, proanthocyanidins, and flavonoids, which have demonstrated antioxidant and anti-inflammatory properties. Several preclinical studies (primarily in vitro and in animal models) have investigated the potential gastroprotective effects of grape extracts against ulcers induced by factors like ethanol, non-steroidal anti-inflammatory drugs (NSAIDs), or stress. These studies suggest that grape polyphenols may help reduce gastric mucosal damage by scavenging free radicals, enhancing mucosal defense mechanisms, and reducing inflammation. For example, grape seed extract has been shown in rats to decrease ulcer formation and improve healing, possibly by upregulating protective mucus and modulating local inflammatory responses.

However, robust clinical evidence in humans is lacking. Most available studies are preclinical, and well-designed randomized controlled trials in humans are needed to confirm efficacy and determine appropriate dosing and safety. While grapes have a long history of use in traditional medicine for a range of ailments, their direct application for ulcers is primarily supported by modern pharmacological studies rather than historical use. Therefore, the evidence supporting the use of grape for ulcer treatment is preliminary and should be considered suggestive but not conclusive.

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Products containing grape

Health Concerns

Brands

Evidence supporting the use of: Grape
For the health condition: Ulcers

Table of Contents

Synopsis

Other ingredients used for Ulcers

Other health conditions supported by grape

Products containing grape

Health Concerns

Brands

Evidence supporting the use of: GrapeFor the health condition: Ulcers

Table of Contents

Synopsis

Other ingredients used for Ulcers

Other health conditions supported by grape

Products containing grape

Evidence supporting the use of: Grape
For the health condition: Ulcers