Evidence supporting the use of: L-glutathione
For the health condition: Ulcers

Links: Go back one page, Tool main page, Ingredients list, Health conditions list, Body systems list

Synopsis

Source of validity: Scientific
Rating (out of 5): 2

L-glutathione has some scientific basis for its potential use in supporting the treatment or prevention of ulcers, particularly gastric ulcers. Glutathione is a tripeptide composed of glutamine, cysteine, and glycine and is a major endogenous antioxidant in cells. Its main function is to protect tissues from oxidative stress, which is implicated in the pathogenesis of gastric mucosal injury and ulcer formation. Some animal studies have shown that depletion of glutathione in the gastric mucosa increases susceptibility to damage from non-steroidal anti-inflammatory drugs (NSAIDs), alcohol, and stress, while supplementation or preservation of glutathione levels may confer protective effects. For example, research has demonstrated that glutathione administration in rats reduces the severity of ethanol-induced gastric lesions by scavenging free radicals and supporting mucosal defense mechanisms.

However, direct clinical trials in humans using oral L-glutathione to treat or prevent peptic ulcers are extremely limited or lacking. Most human data focus on the general importance of antioxidants or on glutathione precursors (like N-acetylcysteine) rather than glutathione itself. Furthermore, oral bioavailability of L-glutathione is debated, as it may be broken down in the gut before reaching systemic circulation. While the theoretical rationale and animal evidence are promising, current scientific validation in humans is weak, placing the evidence at a 2 on the scale. Therefore, while some scientific rationale exists, L-glutathione is not a mainstream or well-established therapy for ulcers.

More about l-glutathione
More about Ulcers

Other ingredients used for Ulcers

cutch
akkermansia muciniphila
alfalfa
aloe vera
annatto
anthocyanins
apple
apricot
arjun tree
astragalus
bacillus coagulans
bacillus subtilis
bamboo
barberry
barley
berry flavor
Beta-Glucan
bifidobacterium bifidum
bifidobacterium lactis
bifidobacterium longum
bilberry
black currant
black garlic
bupleurum falcatum
butyrate triglyceride
caterpillar mushroom
cauliflower
chaga mushroom
champignon
chicory
colostrum
curcumin
cuspidatum root
d-alpha tocopherol
diallyl disulfide (DADS)
dong quai root
melon
epigallocatechin gallate (EGCG)
fennel
flaxseed
gentian root
grape
green banana
green tea
heartwood
hesperetin
Indian gum arabic tree
honeysuckle
knotweed
Japanese sophora
jujube
l-carnosine
l-cysteine
l-glutathione
lactobacillus acidophilus
lactobacillus brevis
lactobacillus bulgaricus
lactobacillus casei
lactobacillus fermentum
lactobacillus gasseri
lactobacillus paracasei
lactiplantibacillus plantarum
lactobacillus salivarius
lactococcus lactis
licorice root
luteolin
mango
mangosteen
marshmallow
melatonin
methylmethionine sulfonium chloride (vitamin U)
mint
n-acetyl-glucosamine
oat
okra
oleanolic acid
olive
pectin
perilla
phospholipids
pine bark
platycodon root
pomegranate
pomelo
pumpkin
quail egg
quercetin
redcurrant
rehmannia glutinosa
resveratrol
rhubarb root
rose hips
sage
slippery elm bark
spirulina
sulforaphane glucosinolate
tocotrienols
tributyrin
vitamin C
watercress
wheat grass
whey protein
mulberry
zinc
bentonite
sarsaparilla
yellow root
cardamom
neem tree
enicostemma littorale
pterocarpus marsupium
alpinia galangal
anise
pistacia integerrima gall
holarrhena antidysenterica
fumaria parviflora
picrorhiza kurroa
rubia cordifolia
swertia
bee pollen
blessed thistle
lingzhi
yarrow
prickly ash
elecampane
broomrape
flowering quince
dogwood
lotus seed
birch
sodium alginate
sheep's sorrel
queen of the meadow
caraway
purslane
wood betony
biota seed
goji berry
white oak
alginic acid
algae
ashitaba
3-(4-hydroxy-3-methoxyphenyl)prop-2-enoic acid
Arugula
akebia
Agastache
Autumn elaeagnus
Ardisia
acacia
Agave
Agrimony
Apigenin
Aronia melanocarpa
Antrodia camphorata
Achyranthes
Abrus
Alchornea
American Pawpaw
Amomum
Asarum heterotropoides
Albizia
Alchemilla
Asafoetida
Aucubin
Anserina
Asam gelugor
Astragaloside
Arrowroot
anthocyanidins
Andrographis
Alsonia scholaris
Agrimonia pilosa
Acemannan
Algin
Anemarrhena
Abuta
Alstonia macrophylla
Amor seco
Arani
Arisaema
Astragalin
Buttermilk
Bermuda Grass
Bai Ji
Baliospermum
Baphicacanthus cusia
Blackthorn
bergenin
Betulinic acid
Bicarbonate
Blepharis
Brassica
Boswellic Acid
Belleric myrobalan
Bistort
Big Quaking Grass
Baicalein
Bael
Bloodroot
Butternut
Basidiomycota
boldo
Black Gram
Boswellia
Bethroot
Banyan
Barbasco
Bitter principals
banana
Baobab
Bifidobacteria
Bupleurum
bacoside
Baicalin
Buckwheat
Belamcanda
Bergenia
Bignay
Bottle gourd
Caffeic Acid
Cumin
Centaury
Centella triterpenes
Casearia esculenta
Croton seeds
Carqueja
Catalpol
Chebulic acid
Coriander
Clerodendrum phlomidis
Carvacrol
Cape Aloe
Centaurium erythraea
Cyanidin
Cruciferous
Catechu
Centella asiatica
Celandine
Cinnamic Acid
Chard
Cinidium
Campylandra fimbriata
Colombo
Corktree
Cubeb
C-Phycocyanin
Carob
Cabbage
Cranesbill
Carlina
Calamus
Chestnut
Chebulinic acid
Corilagin
Cynodon dactylon
Cassava
Chiococca alba
Cynanchum
Casearia sylvestris
Carnosic acid
Didymocarpus
Dwarf Morning Glory
Date
David's Milkberry
epicatechin
Emblicanin
Endive
Ellagitannin
Emodin
Fig
Goldthread
Glycine
Lotus
Molasses
Oak
Orchid
Prickly Pear Cactus
Quince
Rose
Rhubarb
Snakeroot (unspecified)
walnut

Products containing l-glutathione

Thorne Advanced Digestive Enzymes Bio-Gest
Designs For Health Amino-D-Tox™
Designs For Health Amino-D-Tox™
Metagenics BioPure Protein® Powder
Metagenics Bone Builder Active
Integrative Therapeutics Detoxication Factors
Metagenics Echinacea Synergy
Douglas Laboratories Free Form Amino
Integrative Therapeutics Glutathione Cell Defense
Thorne Glutathione-SR NSF
Metagenics ImmuCore
Metagenics Immune Defense Pack
Integrative Therapeutics K-PAX MitoNutrients
Designs For Health L-Glutathione Power™
Pure Encapsulations Liposomal Glutathione
Pure Encapsulations Liposomal Glutathione
Designs For Health Liposomal Glutathione
Douglas Laboratories Liposomal Glutathione
Pure Encapsulations Liposomal Glutathione
Pure Encapsulations Macular Support Formula
Pure Encapsulations Macular Support Formula
Thorne MediClear Plus
Designs For Health Metal-X-Synergy™
Designs For Health NOx Synergy™
Designs For Health PaleoCleanse Plus™
Designs For Health PaleoCleanse Plus™
Designs For Health PaleoCleanse Plus™ Detox Program
Designs For Health PaleoCleanse Plus™Chocolate Detox Kit
Integrative Therapeutics Panplex 2-Phase
Metagenics Perfect Protein® Pea & Rice Chocolate Powder
Metagenics Perfect Protein Pea & Rice Vanilla Powder
Metagenics Perfect Protein Whey Chocolate
Metagenics Perfect Protein Whey Vanilla
Designs For Health Plant Protein Cleanse
Designs For Health Plant Protein Cleanse Plus™ 570g
Vitabase Prostate Complex (Formerly Prostate Complete)
Designs For Health Prostate Supreme™
Designs For Health Prostate Supreme™
Integrative Therapeutics ProThrivers Wellness Flav Complex
Pure Encapsulations Reduced Glutathione
Pure Encapsulations Reduced Glutathione
Designs For Health S-Acetyl Glutathione Synergy
Vitabase Super Antioxidant Formula
Metagenics Ultra Glucose Control® Chocolate
Metagenics Ultra Glucose Control Chocolate
Metagenics Ultra Glucose Control Vanilla
Metagenics Ultra Glucose Control Vanilla
Metagenics Ultra Potent-C 500
Metagenics Ultra Potent-C Powder
Metagenics Ultra Prostagen Concentrated
Pure Encapsulations Ultra Pure Pack
Metagenics UltraGI Replenish® Chocolate
Metagenics UltraGI Replenish Chocolate
Metagenics UltraGI Replenish Vanilla
Metagenics UltraGI Replenish Vanilla
Metagenics UltraInflamX Plus 360°® Chocolate/Orange
Metagenics UltraInflamX Plus 360° Mango
Metagenics UltraInflamX Plus 360° Mango
Metagenics UltraInflamX Plus 360° Orange
Metagenics UltraInflamX Plus 360° Original Spice
Metagenics UltraInflamX Plus 360° Pineapple/Banana
Metagenics UltraInflamX Plus 360° Pineapple/Banana
Metagenics UltraMeal Advanced Protein® Dutch Chocolate
Metagenics UltraMeal Advanced Protein French Vanilla
Metagenics UltraMeal Advanced Protein Plain
Metagenics UltraMeal Cardio 360°® Pea/Rice Chocolate
Metagenics UltraMeal Cardio 360° Pea/Rice Vanilla
Pure Encapsulations UltraNutrient®
Pure Encapsulations UltraNutrient®
Pure Encapsulations UltraNutrient®
Douglas Laboratories Uro-Pro ®
Vitabase Vision Support