Evidence supporting the use of: Licorice root
For the health condition: Ulcers

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Licorice root (Glycyrrhiza glabra) has a long history of use in traditional medicine for digestive complaints, including ulcers. Modern research provides some scientific validation for its use in supporting and treating peptic ulcers, especially in the form of deglycyrrhizinated licorice (DGL), which minimizes side effects associated with whole licorice. Several studies have found that licorice root and DGL may help protect the stomach lining by increasing mucus production, stimulating cell regeneration, and inhibiting the growth of Helicobacter pylori, the bacterium often implicated in ulcer formation. Clinical trials and animal studies have demonstrated that DGL can reduce ulcer size and accelerate healing, likely due to its anti-inflammatory and cytoprotective effects.

However, the evidence is not as robust as that for conventional treatments like proton pump inhibitors or antibiotics. Most studies are small, and more high-quality, large-scale clinical trials are needed to fully establish licorice root’s efficacy and safety profile. Still, licorice root remains a popular adjunct therapy in integrative medicine for ulcer management, especially for those seeking natural approaches or who have contraindications to standard medications. It is important to note that whole licorice root, when consumed in large amounts or over long periods, can cause significant side effects such as hypertension and hypokalemia due to its glycyrrhizin content; hence, DGL is preferred for ulcer support.

More about licorice root
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Other ingredients used for Ulcers

3-(4-hydroxy-3-methoxyphenyl)prop-2-enoic acid
Abrus
Abuta
Acacia
Acemannan
Achyranthes
Agastache
Agave
Agrimonia pilosa
Agrimony
Akebia
Akkermansia muciniphila
Albizia
Alchemilla
Alchornea
Alfalfa
Algae
Algin
Alginic acid
Aloe vera
alpinia galangal
Alstonia macrophylla
Alstonia scholaris
American Pawpaw
Amomum
Amor seco
Andrographis
Anemarrhena
anise
annatto
Anserina
anthocyanidins
anthocyanins
Antrodia camphorata
apigenin
apple
apricot
Arani
Ardisia
Arisaema
arjun tree
Aronia melanocarpa
arrowroot
arugula
asafoetida
Asam gelugor
Asarum heterotropoides
ashitaba
astragalin
astragaloside
astragalus
aucubin
Autumn elaeagnus
bacillus coagulans
bacillus subtilis
bacoside
bael
bai ji
baicalein
baicalin
Baliospermum
bamboo
banana
banyan
baobab
Baphicacanthus cusia
barbasco
barberry
barley
Basidiomycota
bee pollen
Belamcanda
belleric myrobalan
bentonite
Bergenia
bergenin
bermuda grass
beta-glucan
bethroot
betulinic acid
bicarbonate
Bifidobacteria
Bifidobacterium bifidum
Bifidobacterium lactis
Bifidobacterium longum
big quaking grass
bignay
bilberry
biota seed
birch
bistort
bitter principals
black currant
black garlic
black gram
blackthorn
Blepharis
blessed thistle
bloodroot
boldo
Boswellia
Boswellic Acid
bottle gourd
Brassica
broomrape
Buckwheat
Bupleurum
bupleurum falcatum
buttermilk
butternut
butyrate triglyceride
C-phycocyanin
cabbage
caffeic Acid
calamus
Campylandra fimbriata
cape aloe
caraway
cardamom
Carlina
carnosic acid
carob
carqueja
carvacrol
Casearia esculenta
Casearia sylvestris
cassava
catalpol
catechu
caterpillar mushroom
cauliflower
celandine
Centaurium erythraea
centaury
Centella asiatica
Centella triterpenes
chaga mushroom
champignon
chard
chebulic acid
chebulinic acid
chestnut
chicory
Chiococca alba
Cinidium
cinnamic acid
Clerodendrum phlomidis
colombo
colostrum
coriander
corilagin
corktree
cranesbill
croton seeds
cruciferous
cubeb
cumin
curcumin
cuspidatum root
cutch
cyanidin
Cynanchum
Cynodon dactylon
d-alpha tocopherol
date
David\'s milkberry
diallyl disulfide (DADS)
Didymocarpus
dogwood
dong quai root
dwarf morning glory
elecampane
ellagitannin
emblicanin
emodin
endive
Enicostemma littorale
epicatechin
epigallocatechin gallate (EGCG)
false calumba
fennel
ficin
fig
flavanones
flavones
flaxseed
fleabane
flowering quince
frankincense
Fumaria parviflora
fumitory
Gac
galangin
gallic acid
garcinol
garden cress
Gardenia jasminoides
Gelidiella acerosa
genipap
gentian
gentian root
Gentiana calycosa
Gentiana manshurica
geraniol
Glucosinolates
Glutamine
Glycine
Glycosaponin
Glycyrrhetinic acid
Glycyrrhizin
goji berry
golden shower tree
goldthread
grape
green banana
green tea
Guazuma ulmifolia
Gypenoside
heartwood
Hemidesmus
hericium mushroom
hesperetin
holarrhena antidysenterica
honey loquat syrup
honeybush
honeysuckle
Houttuynia
huckleberry
hydroxycinnamic acid
Hyperoside
Indian gum arabic tree
Indian sarsparilla
Isoalantolactone
isoliquiritigenin
isothiocyanates
Japanese sophora
Jatoba
Java brucea
Javanese Long Pepper
jujube
Jurubeba
Kaempferol
Kefiran
knotweed
Kombucha
kuding tea
Kutkins
L-carnosine
L-cysteine
L-glutathione
L. lactis
lactiplantibacillus plantarum
Lactobacillus
Lactobacillus acidophilus
Lactobacillus brevis
Lactobacillus bulgaricus
Lactobacillus casei
Lactobacillus fermentum
Lactobacillus gasseri
Lactobacillus johnsonii
Lactobacillus kefiranofaciens
Lactobacillus paracasei
Lactobacillus plantarum
Lactobacillus salivarius
Lactococcus lactis
Lactococcus rhamnosus
Land Cress
Large-leaf gentian
Leptadenia
leucoanthocyanidins
licorice root
Ligustrum
limonene
limonoid
Lindera
lingzhi
liverwort
longan
Lophira lanceolata
Loranthus
lotus
lotus seed
luteolin
Lysimachia
mango
mangosteen
mangostene xanthone
manzanita
Marine protein
Marjoram
Marking Nut Tree
Marshmallow
Matico
Maytenus ilicifolia
Meadowsweet
Melatonin
Melon
Mesquite
Mesua
Methylmethionine sulfonium chloride (vitamin U)
Mezoneuron benthamianum
Microtea debilis
Millet
Millettia
Mint
Molasses
Mondo grass
Mucilage
Mulberry
Mung bean
Myricetin
N-acetyl-glucosamine
Nardostachys
Natsudaidai
Neem tree
Night jessamine
Oak
oat
okra
oleanolic acid
olive
Operculina turpethum
Opuntia streptacantha
orchid
Osthole
Oxymatrine
parasol mushroom
Pedra hume
Pentatropis capensis
Pepper Bark Tree
perilla
Persimmon
phospholipids
picrorhiza kurroa
Pimpinella
pine bark
Pinellia ternata
Piper chaba
Piper retrofractum
pistacia integerrima gall
platycodon root
Plumbago zeylanica
Polydatin
Polypodium
pomegranate
pomelo
prickly ash
Prickly Pear Cactus
Prosopis
Pterocarpus marsupium
pumpkin
purslane
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quail egg
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queen of the meadow
quercetin
quince
Rehmannia
rehmannia glutinosa
resveratrol
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rhubarb
rhubarb root
Rhus coriaria
Rosa roxburghii
rose
rose hips
Rubia cordifolia
Rubus
S-Methylmethionine
sage
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saponins
Sarivan
sarsaparilla
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Scoparia dulcis
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Servicetree
Sesquiterpenic Acid
sheep's sorrel
Shen Qu
Shikonin
Shilajit
Silybum
Simaruba
slippery elm bark
Snakeroot
Solanum anguivi
Southernwood
Speedwell
Spilanthes
spirulina
Stachytarpheta cayennensis
sulforaphane glucosinolate
Swertia
Takuna
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tocotrienols
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tributyrin
Ulmus
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vitamin C
Walnut
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wheat grass
Whey protein
White oak
Withanolides
Wood betony
Xanthone
Yarrow
Yellow Dock
Yellow Nut Sedge
Yellow root
Yellow-Fruit Nightshade
Yuzu
Zinc

Other health conditions supported by licorice root

Abdominal Pain
Abrasions
Abscesses
Acid Indigestion
Acne
Addictions (general remedies for)
Addictions (tobacco smoking or chewing)
Addison's Disease
Adenitis
Adrenal Fatigue
Afterbirth Pain
Age Spots
Allergies (respiratory)
Amenorrhea
Anal Fistula or Fissure
Anemia
Appetite (deficient)
Asthma
Autoimmune Disorders
Bronchitis
Canker Sores
Chemotherapy (reducing side effects)
Chicken Pox
Cholera
Chronic Obstructive Pulmonary Disorder
Cirrhosis of the Liver
Cold Sores
Colds (antiviral)
Colds (decongestant)
Colds (general)
Colds (prevention)
Colds (with fever)
Colic (adults)
Colic (children)
Colitis
Colon (atonic)
Colon (spastic)
Congestion
Congestion (bronchial)
Congestion (lungs)
Congestion (lymphatic)
Congestion (sinus)
Constipation (adults)
Contagious Diseases
Convalescence
Cough (damp)
Cough (dry)
Cough (general)
Cough (spastic)
Cramps (menstrual)
Crohn's Disease
Croup
Cushing's Disease
Cytomealovirus
Dyspepsia
Eczema
Emphysema
Endometriosis
Enteritis
Epstein Barr Virus
Estrogen (low)
Fatty Liver Disease
Fever
Fibrosis
Gall Bladder (sluggish or removed)
Gall Stones
Gas and Bloating
Gastritis
Gingivitis
Glands (swollen lymph)
Goiter
Gonorrhea
Gout
Grave's Disease
Hair (loss or thinning)
Hair Care (general)
Halitosis
Hangover
Headache (general)
Headache (sinus)
Headache (tension)
Heart (weakness)
Hemorrhoids
Hepatitis
Hernias
Herpes
Hiatal Hernia
Hiccups
Hot Flashes
Hypotension
Hypothyroid
Impetigo
Indigestion
Infection
Infection (bacterial)
Infection (viral)
Inflammation
Inflammatory Bowel Disorders
Influenza
Injuries
Itching
Itching Ears
Jaundice (adults)
Jock Itch
Kidney Infection
Laryngitis
Leaky Gut Syndrome
Leprosy
Lesions
Leucorrhea
Liver Detoxification
Lungs (fluid in)
Lyme Disease
Lymph Nodes or Glands (swollen)
Malaria
Mastitis
Measles
Menopause
Menorrhagia
Menstrual Irregularity
Menstruation (scant)
Mental Illness
Metabolic Syndrome
Mononucleosis
Mood Swings
Morning Sickness
Mumps
Nausea and Vomiting
Nephritis
Nervous Exhaustion
Nervousness
Night Sweating
Nocturnal Emission
Oral Surgery
Ovarian Pain
Overacidity
Pertussis
Pleurisy
PMS (general)
Pneumonia
Poison Ivy or Oak
Rashes and Hives
Rosacea
Sore Throat
Ulcers