Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Phenolic acids, a class of polyphenolic compounds found in many plant foods such as berries, coffee, and whole grains, have been studied for their potential role in supporting the urinary system, particularly in relation to urinary tract infections (UTIs). The most notable phenolic acid in this context is ellagic acid and hydroxycinnamic acids found in cranberries and other berries. Scientific studies suggest that phenolic acids can inhibit the adhesion of Escherichia coli (E. coli) bacteria to the urinary tract lining, thereby reducing the risk of infection. This anti-adhesive property is primarily attributed to the presence of certain phenolics, including proanthocyanidins, but phenolic acids also contribute to the overall effect.

Systematic reviews and laboratory studies have shown that phenolic-rich extracts can reduce bacterial colonization and inflammation in urinary tissues. However, most evidence comes from in vitro and animal research, with fewer large-scale human clinical trials. Nonetheless, some human studies with cranberry products (containing a mixture of phenolic acids and other polyphenols) have demonstrated a modest reduction in UTI recurrence, especially among women.

In summary, there is a moderate level of scientific evidence supporting the use of phenolic acids, particularly as part of polyphenol-rich foods, in promoting urinary tract health. The effect appears to be primarily preventive rather than therapeutic, and further research is needed to isolate the specific contribution of phenolic acids apart from other related compounds.

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Douglas Laboratories Ultra Preventive 50+ -EZ Swallow