Evidence supporting the use of: Akebia (unspecified)
For the health condition: Urinary Tract Infections

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Akebia, specifically Akebia quinata or Akebia trifoliata, is primarily used in Traditional Chinese Medicine (TCM) under the name "Mu Tong." In TCM, Mu Tong is believed to promote urination and clear heat, and is often used in herbal formulas for urinary tract infections (UTIs), painful urination, or related syndromes described as "Lin Zheng." The plant is thought to have diuretic and anti-inflammatory effects according to traditional theory, although its mechanism is explained within the framework of TCM, not modern biomedical science.

Modern scientific evidence supporting Akebia’s efficacy for UTIs is limited and of low quality. Few pharmacological studies have examined its effects, and those that exist are generally in vitro, animal studies, or focus on related symptoms rather than clinical UTIs. Some constituents of Akebia have demonstrated mild anti-inflammatory or diuretic actions in laboratory settings, but there is no robust clinical trial data in humans confirming its effectiveness for preventing or treating UTIs. Additionally, there are safety concerns: some commercial preparations have been adulterated with Aristolochia species, which contain nephrotoxic and carcinogenic aristolochic acids.

In summary, Akebia is used for UTIs based on traditional herbal practice rather than scientific validation. Its use should be approached with caution, and there is insufficient modern evidence to conclusively support its benefit for urinary tract infections.

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