Angelica archangelica, commonly known as garden angelica, has a long history of traditional use in European herbal medicine. Historical texts and ethnobotanical records indicate that the roots and seeds of Angelica were used for a variety of ailments, including digestive complaints, respiratory issues, and as a diuretic. Its use for urinary tract infections (UTIs) is primarily based on its role as a diuretic and mild antiseptic in folk medicine, intended to promote urination and "flush out" the urinary tract.

However, scientific evidence specifically supporting Angelica archangelica for UTIs is limited. While some in vitro studies report that extracts of Angelica archangelica possess antimicrobial properties, these studies do not directly assess its efficacy against common UTI pathogens (such as Escherichia coli) in humans, nor do they address clinical outcomes. Most clinical and pharmacological studies on Angelica focus on its effects on the gastrointestinal or respiratory systems rather than the urinary tract. Additionally, modern herbal references sometimes mention Angelica as a supportive herb for urinary issues, but usually in the context of its traditional diuretic effect rather than as a primary treatment for infection.

In summary, the use of Angelica archangelica for UTIs is rooted in traditional European herbal medicine, but current scientific validation is lacking, and no high-quality clinical trials confirm its effectiveness for this indication.