Evidence supporting the use of: Lactiplantibacillus plantarum
For the health condition: Urinary Tract Infections

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Lactiplantibacillus plantarum (formerly Lactobacillus plantarum) has been studied for its potential role in supporting urinary tract health, including the prevention and management of urinary tract infections (UTIs). The scientific rationale is based on the probiotic’s ability to modulate the vaginal and urinary microbiota, promote colonization resistance against uropathogens (such as Escherichia coli), and enhance mucosal immune responses. Several in vitro and animal studies have shown that L. plantarum can inhibit the growth and adhesion of common UTI-causing bacteria through the production of organic acids, hydrogen peroxide, and bacteriocins.

However, the direct clinical evidence in humans is limited. Most robust clinical trials on probiotics for UTI prevention have focused on other species, particularly Lactobacillus rhamnosus and Lactobacillus reuteri. Some small-scale studies and pilot trials have included L. plantarum in multi-strain formulas and reported reduced recurrence of UTIs, but isolating the effect of L. plantarum alone is challenging. Systematic reviews and meta-analyses note a potential benefit of probiotics in general for recurrent UTI prevention, but emphasize that specific evidence for L. plantarum is still emerging and not as strong as for other strains.

In summary, the use of L. plantarum for UTIs is justified by limited scientific evidence, mostly from mechanistic studies and preliminary clinical reports. More high-quality, strain-specific clinical trials are needed to confirm its efficacy for UTI prevention or treatment.

More about lactiplantibacillus plantarum
More about Urinary Tract Infections

Other ingredients used for Urinary Tract Infections

Abrus
Abuta
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Adzuki bean
Aerva lanata
Agave
Agrimonia pilosa
Agrimony
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apple cider vinegar
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astragalus
aucubin
bacillus subtilis
bael
baicalin
baobab
barberry
Bauhinia
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berberine
Berberis (unspecified)
Bergenia
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black gram
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buchu
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carvacrol
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coix
coriander
corn
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couch grass
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cubeb
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Cynodon dactylon
D-mannose
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dong quai root
dwarf morning glory
echinacea purpurea
elderberry
Euryale seed
fennel
fenugreek
fleabane
fruit blend (proprietary)
fu ling
Galium
goji berry
gokhru
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gravel root
Graviola
green tea
Guazuma ulmifolia
heather
hibiscus
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horse gram
Houttuynia
hydrangea
hydroxyquinoline
Indian gum arabic tree
Java tea
Job\'s tears
juniper berries
Kachnar
knotgrass
knotweed
lactiplantibacillus plantarum
Lactobacillus
Lactobacillus acidophilus
Lactobacillus brevis
Lactobacillus casei
Lactobacillus crispatus
Lactobacillus fermentum
Lactobacillus gasseri
Lactobacillus jensenii
Lactobacillus paracasei
Lactobacillus pentosus
Lactobacillus plantarum
Lactobacillus rhamnosus
Lactobacillus salivarius
Lactococcus rhamnosus
Lespedeza capitata
lime
lingonberry
Lomatium
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lophatherum leaf
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Stachytarpheta cayennensis
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vitamin C
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