Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Lactobacillus fermentum is a species of probiotic bacteria found in the human microbiota, particularly in the gastrointestinal and urogenital tracts. Its use in supporting or treating Urinary Tract Infections (UTIs) is primarily based on emerging scientific evidence rather than traditional medicine. Several studies have investigated the potential of Lactobacillus strains, including L. fermentum, to prevent recurrent UTIs, especially in women. The rationale is that these beneficial bacteria can help restore and maintain a healthy balance of the vaginal and urinary microbiome, inhibiting the growth of pathogenic bacteria such as Escherichia coli—the most common cause of UTIs.

Research has shown that Lactobacillus fermentum can produce lactic acid and other substances that lower the pH, creating an environment less conducive to pathogenic bacteria. Some clinical trials using probiotic preparations containing Lactobacillus species (though more commonly L. rhamnosus and L. crispatus) have demonstrated a reduction in UTI recurrence rates. However, studies specifically on L. fermentum remain limited, and most evidence comes from in vitro experiments or small-scale human studies with mixed results. Systematic reviews suggest that probiotics may offer modest benefit in UTI prevention, but further high-quality randomized controlled trials are needed to confirm the efficacy of L. fermentum.

In summary, while there is some scientific support for the use of Lactobacillus fermentum in the context of UTI prevention, the evidence is still considered preliminary and not robust enough for widespread clinical recommendation. The rating reflects limited but promising scientific data.

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