Evidence supporting the use of: Oldenlandia
For the health condition: Urinary Tract Infections

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Oldenlandia, particularly Oldenlandia diffusa (also known as Hedyotis diffusa), has a long history of use in traditional medicine systems such as Traditional Chinese Medicine (TCM) and Ayurveda. In these traditions, the plant is valued for its "heat-clearing" and detoxifying properties, and is commonly prescribed for various infections, including urinary tract infections (UTIs). The traditional rationale is that Oldenlandia can help "clear damp heat," a concept in TCM often associated with infections of the urinary tract.

However, contemporary scientific evidence to support its efficacy specifically for UTIs is limited. Some in vitro studies have demonstrated that extracts of Oldenlandia diffusa possess antibacterial properties against certain pathogens, including common UTI-causing bacteria such as Escherichia coli. These findings provide some pharmacological rationale for its traditional use, but clinical trials in humans are lacking. Most research on Oldenlandia focuses on its potential anticancer, anti-inflammatory, or general antimicrobial effects, rather than its direct impact on urinary tract infections.

In summary, the use of Oldenlandia for UTIs is primarily justified by traditional historical usage rather than strong modern scientific validation. While preclinical studies suggest possible antimicrobial properties, high-quality clinical evidence is insufficient, and more rigorous studies are needed to confirm its safety and efficacy for this specific condition.

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