Evidence supporting the use of: Phyllanthus fraternus
For the health condition: Urinary Tract Infections

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Phyllanthus fraternus, commonly known as a close relative of Phyllanthus niruri (“stonebreaker”), has a longstanding presence in traditional medicine systems, particularly in Ayurveda and folk medicine across India and Southeast Asia. It has been traditionally used to manage urinary tract conditions, including urinary tract infections (UTIs), kidney stones, and dysuria. The rationale for its use is based on its reputed diuretic, antimicrobial, and anti-inflammatory properties, which are believed to help flush bacteria from the urinary tract and soothe irritation.

While several studies have investigated the antimicrobial and anti-urolithiatic (anti-kidney stone) properties of the broader Phyllanthus genus, most scientific research focuses on Phyllanthus niruri rather than P. fraternus specifically. Some in vitro studies have suggested that extracts of Phyllanthus species can inhibit the growth of certain uropathogenic bacteria, but robust clinical trials in humans are lacking. There is also some evidence pointing to anti-inflammatory and diuretic effects in animal models. However, the direct application of these findings to the treatment or prevention of UTIs in humans remains largely unconfirmed.

In summary, the use of Phyllanthus fraternus for UTIs is primarily supported by traditional use with limited scientific validation. The overall quality and quantity of evidence currently rates as low (2/5), indicating that while traditional practices persist, strong scientific endorsement is not yet established.

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