Evidence supporting the use of: Daidzein
For the body system: Uterus

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Daidzein is an isoflavone found predominantly in soybeans and other legumes. It is classified as a phytoestrogen due to its ability to bind to estrogen receptors, albeit with much weaker activity than endogenous estrogens. The scientific rationale for daidzein's use in supporting the uterus is primarily linked to its potential to modulate estrogenic activity in the body, which may influence uterine function. Some studies have investigated the effects of soy isoflavones, including daidzein, on menopausal symptoms, endometrial thickness, and uterine health. For example, limited clinical trials suggest that isoflavone supplementation does not significantly increase endometrial thickness or cancer risk in postmenopausal women, implying a degree of safety. However, evidence that daidzein or related isoflavones provide direct benefit to uterine health—such as enhancing uterine function or treating uterine disorders—is weak and mostly indirect. The majority of available studies are either observational, use mixed isoflavones (not daidzein alone), or show only modest effects. There is some traditional use of soy products for women’s health in East Asian populations, but this is not specific to the uterus. In summary, while there is a plausible mechanism and some supporting data, robust clinical evidence for daidzein’s specific benefit to the uterus is limited, and more research is needed to draw firm conclusions.

More about daidzein
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Products containing daidzein

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