Evidence supporting the use of: Estrogen
For the body system: Uterus

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Table of Contents

Synopsis

Source of validity: Scientific
Rating (out of 5): 5

Estrogen is a key hormone in the female reproductive system and its use to support the uterus is strongly supported by scientific evidence. Estrogen is central in regulating the menstrual cycle and maintaining the structural and functional integrity of the uterus. It stimulates the growth of the endometrial lining during the menstrual cycle, preparing the uterus for possible implantation of an embryo. In clinical practice, estrogen therapy is used to treat various gynecological conditions, such as menopausal symptoms (including vaginal atrophy and endometrial thinning), irregular menstrual cycles, and certain forms of infertility. After menopause, decreased estrogen levels are associated with uterine atrophy and increased risk of endometrial dysfunction. Hormone replacement therapy with estrogen can help counteract these changes. Additionally, in women undergoing assisted reproductive techniques, estrogen is administered to optimize the uterine environment for embryo implantation. The scientific basis for these uses is well established in both animal and human studies, as well as in clinical guidelines. However, estrogen therapy must be carefully managed due to potential risks, such as endometrial hyperplasia if unopposed by progesterone. Overall, the use of estrogen for uterine support is grounded in robust scientific research and decades of clinical experience.

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Products containing estrogen

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