Evidence supporting the use of: Folic acid
For the body system: Uterus

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Synopsis

Source of validity: Scientific
Rating (out of 5): 5

Folic acid (vitamin B9) has strong scientific validation for its use in supporting the uterus, particularly in the context of reproductive and prenatal health. Numerous studies have demonstrated that folic acid supplementation before conception and during early pregnancy significantly reduces the risk of neural tube defects (NTDs) in the developing fetus. While the direct benefit is to the embryo, the uterus is the site of implantation and early development, so maintaining a healthy uterine environment is critical. Adequate folic acid intake is associated with proper cellular division and DNA synthesis, both of which are essential during the rapid growth of uterine and embryonic tissues in early pregnancy. Major health organizations, including the Centers for Disease Control and Prevention (CDC) and the World Health Organization (WHO), recommend folic acid supplementation for women of reproductive age for these reasons. While folic acid's most well-known benefit is in preventing fetal neural tube defects, its role in overall reproductive health, cellular growth, and tissue maintenance also justifies its use in supporting uterine health. There is robust scientific consensus and public health guidance supporting this application, making folic acid one of the few ingredients with a high level of evidence for use in this context.

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