Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Soy isoflavones are phytoestrogens, plant-derived compounds with estrogen-like activity. Their use to support the vaginal body system, particularly for alleviating symptoms of vaginal atrophy and dryness associated with menopause, is primarily justified by scientific evidence, though this evidence is moderate in strength. Several randomized controlled trials and meta-analyses have investigated the efficacy of soy isoflavones in reducing menopausal symptoms, including vaginal dryness. Some studies suggest that soy isoflavones can improve vaginal cytology and moisture in postmenopausal women, likely due to their weak estrogenic effects on vaginal tissue. For example, a 2016 systematic review (Levis et al., Menopause) found modest improvements in vaginal health parameters among women supplementing with isoflavones. However, not all studies report significant benefits, and the overall effect size is generally small compared to standard estrogen therapy. There is limited evidence for benefit in premenopausal women. In summary, while soy isoflavones are not a substitute for prescription hormonal treatments, there is moderate scientific support for their use in supporting vaginal health in postmenopausal women experiencing symptoms due to low estrogen levels.

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