Evidence supporting the use of: Anthocyanidins (unspecified)
For the health condition: Varicose Veins
Synopsis
Source of validity: Scientific
Rating (out of 5): 3
Anthocyanidins, a class of flavonoids found in various fruits and vegetables (notably berries), have been studied for their potential vascular benefits, including the support and treatment of varicose veins. The rationale behind their use lies in their antioxidant, anti-inflammatory, and vasoprotective properties. Several clinical and preclinical studies have demonstrated that anthocyanidins and their glycoside forms (anthocyanins) can strengthen capillary walls, reduce capillary permeability, and improve microcirculation. These effects are believed to result from their ability to protect collagen and elastin in blood vessel walls and to scavenge free radicals, thereby reducing oxidative stress that can weaken veins.
Some human trials, particularly with bilberry extract (rich in anthocyanins), have reported improvements in symptoms such as leg heaviness, edema, and microcirculatory parameters in chronic venous insufficiency—a condition closely related to varicose veins. However, most studies use specific extracts rather than isolated or unspecified anthocyanidins, and sample sizes are often small. Systematic reviews suggest a moderate benefit, but emphasize the need for larger, high-quality randomized controlled trials to confirm efficacy and safety.
In summary, the use of anthocyanidins for varicose veins is supported by plausible mechanisms and some clinical evidence, but the strength of the evidence is moderate rather than robust, and further research is warranted.
More about Anthocyanidins (unspecified)
More about Varicose Veins
Other ingredients used for Varicose Veins
anthocyaninsbeet
butcher's broom
hesperidin
horse chestnut
pine bark
resveratrol
vitamin C
guelder rose
Aescin
anthocyanidins
anthocyanosides
Centella triterpenes
Other health conditions supported by Anthocyanidins (unspecified)
Aging (prevention)Arthritis
Bruises (healing)
Cancer (natural therapy for)
Cancer (prevention)
Cardiovascular Disease
Circulation (poor)
Circulation (to the brain)
Diabetes
Diabetic Retinopathy
Eye Problems
Free Radical Damage
Hypertension
Inflammation
Inflammatory Bowel Disorders
Macular Degeneration
Memory and Brain Function
Metabolic Syndrome
Osteoporosis
Skin Care (general)
Urinary Tract Infections
Varicose Veins
Wounds and Sores