Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Flavanols, a subclass of flavonoids commonly found in cocoa, tea, apples, and other plant-based foods, have been investigated for their potential benefits in managing varicose veins and chronic venous insufficiency (CVI). The scientific rationale for their use is rooted in their antioxidant and vasoprotective properties. Flavanols are believed to enhance endothelial function, reduce inflammation, and improve microcirculatory blood flow, all of which are implicated in the pathogenesis of varicose veins.

Several clinical studies and meta-analyses have assessed the efficacy of flavonoid-rich preparations, such as micronized purified flavonoid fraction (MPFF, often containing diosmin and hesperidin), in reducing symptoms associated with varicose veins, such as leg swelling, heaviness, and pain. These studies generally suggest a modest but statistically significant benefit compared to placebo. The European Society for Vascular Surgery and other clinical guidelines recognize MPFF as an option for symptom relief in CVI and varicose veins. However, it should be noted that much of the clinical evidence pertains to specific flavonoid formulations rather than all flavanol-rich foods or extracts.

In summary, while there is scientific evidence supporting the use of certain flavanol-containing preparations for the symptomatic treatment of varicose veins, the effect size is moderate, and evidence quality varies. The use is supported by modern clinical trials and guidelines, but more high-quality research is needed to strengthen recommendations and clarify the most effective formulations.

More about Flavanols
More about Varicose Veins

Other ingredients used for Varicose Veins

Other health conditions supported by Flavanols

Products containing Flavanols