Evidence supporting the use of: Bioflavonoids (mixture)
For the body system: Veins

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Bioflavonoids are a group of plant-derived compounds commonly found in citrus fruits, berries, and other foods. They are often promoted for vascular health, particularly in supporting the veins and capillaries. Several types of bioflavonoids, such as diosmin, hesperidin, and rutin, are ingredients in dietary supplements designed to support vein function and are sometimes used for conditions like chronic venous insufficiency (CVI) and varicose veins.

Scientific evidence, particularly for purified forms such as diosmin and hesperidin, supports the use of certain bioflavonoids in improving symptoms of venous disorders. Clinical trials and meta-analyses suggest that these compounds can reduce leg swelling, pain, and other symptoms associated with poor vein function. The mechanism is thought to involve strengthening capillary walls, reducing inflammation, and improving lymphatic drainage.

However, it is important to note that much of the clinical research has focused on specific, standardized bioflavonoid extracts rather than mixtures of uncharacterized bioflavonoids. For example, micronized purified flavonoid fraction (MPFF), a mixture of diosmin and hesperidin, has demonstrated efficacy in multiple studies. The evidence for general or unspecified "bioflavonoid mixtures" is less robust, but the association with vascular health is supported by both clinical and mechanistic data for certain key flavonoids.

In summary, there is scientific validation—though mainly for specific, well-studied flavonoids rather than generic mixtures—supporting the use of some bioflavonoids for vein health. The evidence level is moderate (3/5) due to variability in product composition and study quality.

More about Bioflavonoids (mixture)
More about Veins

Other body systems supported by Bioflavonoids (mixture)

Arteries
Blood
Capillaries
Circulatory System
Eyes
Gums
Heart
Immune System
Liver
Skin
Veins

Products containing Bioflavonoids (mixture)

We currently have no products on Vitabase that contain this ingredient.