Evidence supporting the use of: Puerain
For the body system: Veins

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Puerarin is an isoflavone compound extracted from the root of the Pueraria lobata plant (commonly known as kudzu). Traditionally used in Chinese medicine, modern research has provided some scientific validation for its use in supporting vascular and venous health. Several preclinical and clinical studies suggest that puerarin has vasodilatory, anti-inflammatory, and antioxidant effects which may be beneficial for the veins and overall circulatory system. In animal models and small clinical trials, puerarin has been shown to improve microcirculation, reduce blood viscosity, and protect endothelial function. These properties are relevant for vein health, potentially aiding in conditions such as chronic venous insufficiency or varicose veins. However, most of the evidence comes from in vitro experiments, animal studies, and limited human trials primarily conducted in Asia. Larger, high-quality randomized controlled trials in humans are still lacking, so while the preliminary data is promising and suggests a biological basis for the use of puerarin in vein support, definitive clinical efficacy remains to be fully established. Therefore, the evidence can be considered moderate, with a rating of 3 out of 5.

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