Evidence supporting the use of: Rue
For the body system: Veins

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Rue (Ruta graveolens) has a long history of use in traditional medicine, particularly in Europe and the Mediterranean, for supporting circulatory health and the veins. Herbalists historically used rue as a remedy for varicose veins, hemorrhoids, and to strengthen capillaries, often incorporating it into topical applications or teas. The rationale behind its use lies in its reputed vasoprotective and anti-inflammatory properties, which were believed to help maintain vein integrity and reduce swelling. However, scientific validation of these traditional claims is limited. While rue contains compounds such as rutin (a flavonoid known for capillary-strengthening effects), the concentration in rue is lower compared to other sources like buckwheat. Furthermore, clinical studies directly investigating rue's effects on venous health in humans are lacking. Most available evidence remains anecdotal or based on historical texts rather than rigorous scientific trials. As such, while rue’s use for veins is primarily justified by tradition and some phytochemical rationale, the overall evidence supporting its effectiveness is modest. Modern herbal practice tends to favor better-studied botanicals for venous support. Caution is also advised with rue, as it can be toxic in high amounts and cause photodermatitis. In summary, rue’s reputation as a venous tonic is rooted more in tradition than in robust scientific evidence.

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