Evidence supporting the use of: Ruscogenins
For the body system: Veins

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Ruscogenins are steroidal saponins found in the plant Ruscus aculeatus (butcher's broom). The use of butcher's broom root extracts to support venous health and treat chronic venous insufficiency (CVI) dates back to traditional European herbal medicine. However, in recent decades, ruscogenins have been studied in clinical settings for their effects on the venous system. Several randomized controlled trials and systematic reviews have indicated that butcher's broom extracts, standardized for ruscogenins, can reduce symptoms of CVI such as leg swelling, heaviness, and discomfort.

The mechanism of action is thought to involve vasoconstrictive effects on venous smooth muscle and reduced capillary permeability, likely mediated by alpha-adrenergic activity. A 2010 Cochrane review concluded that preparations containing ruscogenins may provide a modest benefit for alleviating some CVI symptoms, though the quality of evidence is moderate and more high-quality studies are needed. Additionally, the European Medicines Agency (EMA) recognizes butcher's broom as a traditional herbal medicinal product for minor venous circulatory disturbances.

Overall, there is moderate scientific evidence supporting the use of ruscogenins for venous health, though it is not as robust as for some pharmaceutical interventions. Use is supported both by historical tradition and clinical research, but more large-scale trials are needed to confirm efficacy and safety.

More about Ruscogenins
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Other body systems supported by Ruscogenins

Arteries
Capillaries
Circulatory System
Lymphatics
Veins

Products containing Ruscogenins

We currently have no products on Vitabase that contain this ingredient.