Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Ajoene, a sulfur-containing compound derived from garlic (Allium sativum), has been investigated for its potential antiviral and antiproliferative properties. Its use in the treatment of warts is primarily supported by limited scientific studies rather than long-standing traditional use. One notable clinical study published in 2005 evaluated the topical application of ajoene in patients with common and plane warts. In this open-label trial, 21 patients applied ajoene gel to their warts once daily for 1-2 weeks. The results showed that 83% of patients experienced complete resolution of their warts, with no significant adverse effects reported. The proposed mechanism involves ajoene's interference with viral replication and keratinocyte proliferation, possibly due to its effects on cellular signaling pathways and the immune response.

However, the evidence base remains limited to small-scale studies and case reports, with a lack of large randomized controlled trials. While these preliminary findings are promising and suggest that ajoene may be effective in treating warts, more robust research is needed to confirm its efficacy and safety. In summary, the use of ajoene for warts is justified by early scientific evidence, but its clinical use is not yet well-established or widely endorsed by major medical guidelines.

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