Evidence supporting the use of: Muscle
For the health condition: Wasting

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Synopsis

Source of validity: Scientific
Rating (out of 5): 4

Muscle tissue, particularly in the form of dietary protein (from animal or plant sources), is scientifically validated as a key intervention for treating or supporting muscle wasting (also known as cachexia or sarcopenia). Muscle wasting commonly occurs in conditions such as aging, chronic illness (e.g., cancer, AIDS, chronic kidney disease), and malnutrition. Clinical studies have shown that adequate dietary protein intake, often sourced from muscle meat, is essential for maintaining or rebuilding muscle mass in these conditions. Supplementation with amino acids (the building blocks of muscle protein) or high-quality protein has been demonstrated to stimulate muscle protein synthesis and reduce the rate of muscle loss. Guidelines from organizations such as the European Society for Clinical Nutrition and Metabolism (ESPEN) and the American Society for Parenteral and Enteral Nutrition (ASPEN) recommend increased protein intake for individuals at risk of or experiencing muscle wasting. In addition to protein, muscle tissue is a source of other micronutrients (such as creatine and carnitine) that may further support muscle health. While resistance exercise is also important, dietary intake of muscle-derived protein remains a cornerstone of evidence-based treatment for muscle wasting. Overall, the scientific evidence supporting the use of muscle protein in preventing or treating wasting is strong, with multiple randomized controlled trials and meta-analyses confirming its efficacy.

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