Evidence supporting the use of: Ascophyllum nodosum
For the health condition: Weight Loss

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Ascophyllum nodosum, a brown seaweed, has gained attention as a potential aid for weight loss primarily due to its content of bioactive compounds such as fucoidan, polyphenols, and alginates. Several preclinical and a few clinical studies have investigated its effects on metabolism and body weight. Mechanistically, extracts of A. nodosum are believed to inhibit digestive enzymes like α-amylase and α-glucosidase, potentially reducing carbohydrate absorption and postprandial blood glucose spikes. Additionally, alginates from the seaweed can increase satiety by forming viscous gels in the stomach, which may help reduce calorie intake. A handful of small-scale human studies have reported modest reductions in body weight, body fat, or appetite when A. nodosum extracts are consumed, often in combination with Fucus vesiculosus or other seaweeds. However, these studies are generally short-term, involve small participant numbers, and sometimes lack rigorous controls. Meta-analyses and systematic reviews typically conclude that, while the evidence is promising, it remains preliminary and insufficient for strong recommendations. In summary, while there is a scientific rationale and some early evidence for the use of Ascophyllum nodosum in weight management, the overall quality and quantity of clinical evidence are limited. Thus, its use for weight loss is supported by scientific but not robust evidence, meriting a low-to-moderate rating.

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