Evidence supporting the use of: Ecdysteroids
For the health condition: Weight Loss

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Ecdysteroids, such as ecdysterone, are naturally occurring steroid hormones found in plants and insects. Their use for weight loss is primarily based on preliminary scientific studies rather than a long-standing traditional use. Early studies in animals and limited human trials have suggested that ecdysteroids may help increase muscle mass and improve body composition, potentially through enhanced protein synthesis and anabolic effects. For example, a 2019 double-blind, placebo-controlled study published in Archives of Toxicology found that ecdysterone supplementation in trained athletes led to greater increases in muscle mass and performance compared to placebo. However, direct evidence for fat loss or weight loss is sparse, and most studies have focused on muscle growth rather than reduction of body fat.

There is also interest in ecdysteroids due to their ability to influence metabolism and possibly promote lipolysis (fat breakdown), but robust human data are lacking. The majority of available research involves animal models or cell cultures, with only a few small-scale human studies. No major health organizations endorse ecdysteroids for weight loss, and their long-term safety and efficacy remain unclear. Therefore, while there is some scientific basis for their effect on body composition, the evidence specifically supporting ecdysteroids for weight loss is limited and not definitive.

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