Evidence supporting the use of: Guggul Extract
For the health condition: Weight Loss

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Guggul extract, derived from the resin of the Commiphora mukul tree, has a long history of use in traditional Ayurvedic medicine, primarily for the management of lipid disorders and obesity. In Ayurveda, guggul is believed to possess "medoghna" (fat-destroying) properties and is often included in formulations intended to support weight loss or reduce body fat. The traditional rationale is based on its purported effects on metabolism and its use in treating conditions described as related to excess body weight or fat accumulation.

From a scientific perspective, the evidence supporting guggul's efficacy for weight loss is limited and mixed. Some small clinical trials and animal studies have investigated the effects of guggulsterones—active compounds in guggul—on lipid metabolism and body weight. However, results have been inconsistent, with some studies showing modest effects on cholesterol levels and even fewer demonstrating significant weight loss in humans. Systematic reviews and meta-analyses generally conclude that there is insufficient high-quality clinical evidence to confirm guggul extract's effectiveness for weight reduction. Adverse effects, particularly gastrointestinal complaints and skin rashes, have also been reported. Overall, while guggul is traditionally used for weight loss, robust scientific validation for this use is lacking.

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