Evidence supporting the use of: Gymnemagenin
For the health condition: Weight Loss
Synopsis
Source of validity: Traditional
Rating (out of 5): 2
Gymnemagenin is a bioactive compound found in the plant Gymnema sylvestre, which has a long history of use in traditional Ayurvedic medicine, particularly for supporting glucose metabolism and as an adjunct in weight management. The traditional use of Gymnema sylvestre, and by extension gymnemagenin, stems from its reputed ability to suppress sweet taste perception and reduce sugar cravings, which could indirectly assist with weight loss by lowering caloric intake from sugars. While there is some preliminary scientific research on Gymnema sylvestre extracts in general, most of the available evidence centers around its effects on blood sugar control and not directly on weight loss. There are a few animal studies and small human trials suggesting that Gymnema sylvestre extracts may help reduce body weight and food intake, but these do not isolate gymnemagenin as the active component responsible for these effects. Thus, while the use of Gymnema sylvestre (and potentially gymnemagenin) for weight loss is primarily justified by traditional practice, the direct scientific evidence specifically for gymnemagenin’s effect on weight loss remains limited and inconclusive. More robust clinical trials targeting gymnemagenin alone are needed to establish its efficacy for this purpose.
Other ingredients used for Weight Loss
7-Keto-DHEAacetyl l-carnitine
akkermansia muciniphila
alpha-ketoglutarate (AKG)
apple
ashwagandha
black tea
chia seed
coleus forskohlii
conjugated linoleic acid (CLA)
forskohlii root
garcinia
glucomannan
guarana
hydroxycitric acid
inulin
l-leucine
matcha
medium chain triglycerides (MCT)
monkfruit
prune
quinoa
rye
saffron
sardines
black ginger
soybean
almond fruit
whey protein
jiaogulan
yerba mate
amaranth
millet seed
algae
kidney beans
cocoa
chickpea protein
brown rice protein
AMP-activated protein kinase (AMPK)
1,3,7-Trimethylpurine-2,6-dione
3-desoxy-7-KETO-DHEA
Adrenergic amines
Ascophyllum nodosum
Adzuki bean
Algal protein
Animal protein
Beta-hydroxybutyrate
Beef Protein
Bean
BCAA
Cowpea
California chia
Cardarine
Capsinoids
chlorogenic acid
Capsiate
Chicken
Caralluma fimbriata
Cha de bugre
Diacylglycerol
Dihydrocapsiate
Deoxycholic acid
Egg
Ecdysteroids
Ephedrine
Pistachio
Quinoa Protein
yohimbine
Other health conditions supported by Gymnemagenin
Cholesterol (high)Diabetes
Fat Metabolism (poor)
Sugar Cravings
Weight Loss