Evidence supporting the use of: Stenabolic
For the health condition: Weight Loss

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Stenabolic (SR9009) is a synthetic compound often marketed as an exercise mimetic and is sometimes used off-label by athletes and bodybuilders seeking weight loss or enhanced metabolism. SR9009 acts as an agonist of the Rev-ErbAα nuclear receptor, which plays a role in regulating circadian rhythm, lipid metabolism, and energy homeostasis. Preclinical studies in mice have shown that SR9009 administration can increase metabolic rate, reduce fat mass, and improve endurance even without changes in physical activity or food intake. These effects are attributed to enhanced mitochondrial activity in skeletal muscle and increased energy expenditure.

However, human clinical trials are lacking. There are no published, peer-reviewed studies in humans demonstrating safety or efficacy for weight loss. Most evidence comes from animal studies, which may not fully translate to humans. The compound is not approved by the FDA for any indication, and its use in humans is not supported by regulatory agencies. Additionally, concerns exist regarding the long-term safety profile and potential adverse effects.

In summary, while there is some scientific rationale and promising animal data supporting SR9009’s potential for weight loss, the absence of human studies warrants caution. The evidence is preliminary, and its use cannot be recommended outside of research settings.

More about Stenabolic
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Other health conditions supported by Stenabolic

Energy (lack of)
Fat Metabolism (poor)
Metabolic Syndrome
Weight Loss

Products containing Stenabolic

We currently have no products on Vitabase that contain this ingredient.