Evidence supporting the use of: Thylakoid
For the health condition: Weight Loss

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Thylakoids are membrane-bound compartments inside chloroplasts, primarily found in green plants and algae, and are rich in membrane proteins and pigments. Recent scientific research has investigated the effects of thylakoid supplementation—typically as an extract from spinach—on appetite regulation and weight management. Several randomized controlled trials have shown that dietary thylakoids can delay fat digestion, increase satiety hormones (such as cholecystokinin and GLP-1), and decrease the hunger hormone ghrelin. This results in reduced appetite and a lower caloric intake at subsequent meals. Some clinical studies have reported modest weight loss and improved control of eating in overweight and obese adults who supplement with thylakoids. A notable mechanism is the ability of thylakoids to inhibit pancreatic lipase, thereby slowing down the absorption of dietary fat and promoting the release of satiety hormones. However, while the results are promising, the number of studies is relatively small, most are short-term, and the weight loss observed is modest. There is no significant evidence of traditional use of thylakoids for weight loss, as their application is based on recent scientific developments. Overall, the evidence to support the use of thylakoids for weight loss is moderate but not definitive, warranting a rating of 3 out of 5.

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