Evidence supporting the use of: L-tyrosine
For the health condition: Worry
Synopsis
Source of validity: Scientific
Rating (out of 5): 2
L-tyrosine is an amino acid that serves as a precursor to several important neurotransmitters, including dopamine, norepinephrine, and epinephrine. Its use in supporting "worry"—often interpreted as chronic stress or anxiety—has some scientific basis, though the evidence is not robust enough for high confidence. Several clinical studies have investigated L-tyrosine's ability to support cognitive performance and stress resilience, primarily under conditions of acute stress (such as sleep deprivation, cold exposure, or military training). These studies suggest that L-tyrosine supplementation may help maintain cognitive function during short-term stress by ensuring sufficient neurotransmitter synthesis. However, the direct evidence for L-tyrosine as a treatment for generalized anxiety, worry, or chronic stress in otherwise healthy individuals is limited. Most studies focus on cognitive performance rather than emotional symptoms like worry or anxiety. There is some mechanistic rationale: since stress depletes catecholamine neurotransmitters, and tyrosine helps replenish them, theoretically, it could modulate mood and resilience. Despite this, controlled trials specifically targeting "worry" or anxiety as primary outcomes are scarce. In summary, L-tyrosine has some scientific backing for supporting mental performance under stress, which may indirectly help with stress-related symptoms, but direct evidence for its effectiveness specifically for "worry" is limited. More research is needed before it can be confidently recommended for this purpose.
Other ingredients used for Worry
5-Hydroxytryptophan (5-HTP)ashwagandha
waterhyssop
benegut perilla (proprietary)
damiana
fennel
GABA (gamma aminobutyric acid)
guayusa
kudzu
l-theanine
l-tyrosine
lavender
lion's mane
magnesium
motherwort
ophiopogon root
polygala root
relora® (proprietary)
vitamin B6
zinc
cardamom
1,3,7-Trimethylpurine-2,6-dione
Albizia
Buddha's Hand
bacoside
Poppy
Other health conditions supported by l-tyrosine
Adrenal FatigueApathy
Athletic and Exercise Aids
Attention Deficit Disorder
Depression
Energy (lack of)
Fatigue
Memory and Brain Function
Mood Swings
Nervous Exhaustion
Stress
Worry
Products containing l-tyrosine
Douglas Laboratories
5-HTP Plus Formula
Thorne
Amino Complex Berry
Thorne
Amino Complex Lemon
Pure Encapsulations
Amino-NR
Pure Encapsulations
Amino Replete
Metagenics
BioPure Protein® Powder
Metagenics
Clear Change 10-Day Detox Program with UltraClear RENEW Berry
Metagenics
Clear Change 10-Day Detox Program with UltraClear RENEW Vanilla
Metagenics
Clear Change 28-Day Detox Program with UltraClear RENEW Berry
Metagenics
Clear Change 28-Day Detox Program with UltraClear RENEW Chai
Metagenics
Clear Change 28-Day Detox Program with UltraClear RENEW Vanilla
Pure Encapsulations
Cognitive Aminos
Designs For Health
CraveArrest™
Pure Encapsulations
DopaPlus
Pure Encapsulations
Electrolyte/Energy Formula
Pure Encapsulations
Emotional Wellness
Pure Encapsulations
Emotional Wellness
Douglas Laboratories
Free Form Amino
Pure Encapsulations
Iodine and Tyrosine
Klean Athlete
Klean Isolate ™
Pure Encapsulations
l-Tyrosine
Designs For Health
L-Tyrosine
Designs For Health
Neurolink™
Metagenics
Perfect Protein® Pea & Rice Chocolate Powder
Metagenics
Perfect Protein Pea & Rice Vanilla Powder
Metagenics
Perfect Protein Whey Chocolate
Metagenics
Perfect Protein Whey Vanilla
Vitabase
Super Fat Burner
Thorne
Thyrocsin
Pure Encapsulations
Thyroid Support Complex
Metagenics
Ultra Glucose Control® Chocolate
Metagenics
Ultra Glucose Control Chocolate
Metagenics
Ultra Glucose Control Vanilla
Metagenics
Ultra Glucose Control Vanilla
Metagenics
UltraClear RENEW Detox Powder Berry
Metagenics
UltraClear RENEW Detox Powder Chai
Metagenics
UltraClear RENEW Detox Powder Vanilla
Metagenics
UltraGI Replenish® Chocolate
Metagenics
UltraGI Replenish Chocolate
Metagenics
UltraGI Replenish Vanilla
Metagenics
UltraGI Replenish Vanilla
Metagenics
UltraInflamX Plus 360°® Chocolate/Orange
Metagenics
UltraInflamX Plus 360° Mango
Metagenics
UltraInflamX Plus 360° Mango
Metagenics
UltraInflamX Plus 360° Orange
Metagenics
UltraInflamX Plus 360° Original Spice
Metagenics
UltraInflamX Plus 360° Pineapple/Banana
Metagenics
UltraInflamX Plus 360° Pineapple/Banana
Metagenics
UltraMeal Advanced Protein® Dutch Chocolate
Metagenics
UltraMeal Advanced Protein French Vanilla
Metagenics
UltraMeal Advanced Protein Plain
Metagenics
UltraMeal Cardio 360°® Pea/Rice Chocolate
Metagenics
UltraMeal Cardio 360° Pea/Rice Vanilla