Evidence supporting the use of: Ophiopogon root
For the health condition: Worry

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Ophiopogon root (Ophiopogonis Radix, known as Mai Men Dong in Traditional Chinese Medicine) is traditionally used to nourish yin, moisten the lungs, and calm the spirit (shen). In TCM, “worry” (often associated with anxiety, restlessness, or disturbed shen) can be seen as a result of yin deficiency or dryness affecting the heart and lungs. Classical texts and modern TCM practice sometimes recommend Ophiopogon root as part of formulas intended to address emotional disturbances, including worry, especially when accompanied by symptoms like irritability, insomnia, or palpitations. The plant is thought to provide a gentle, nourishing effect on the heart and mind, supporting emotional stability. However, while this use is well established in traditional practice, there is limited direct scientific evidence specifically linking Ophiopogon root to the treatment of anxiety or worry. Some pharmacological studies suggest potential neuroprotective and anti-stress effects in animal models, but these are preliminary and not directly focused on “worry” as understood in Western medicine. Therefore, the justification for its use in this context is primarily traditional, with modest indirect support from early scientific investigations. As always, individuals should consult a qualified healthcare provider before using herbal remedies for mental health concerns.

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Products containing ophiopogon root

Metagenics Serenagen®
Metagenics Serenagen