Evidence supporting the use of: Rhodiola sacra
For the health condition: Worry

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Rhodiola sacra, a close relative of Rhodiola rosea, has been traditionally used in Tibetan and Chinese medicine to promote resilience against stress, fatigue, and to support mental well-being. The traditional use of Rhodiola species for worry—often characterized as mild anxiety or nervousness—stems from their role as adaptogens, substances believed to help the body adapt to stressors and restore balance. Historical texts and ethnobotanical records indicate that Rhodiola sacra has been used in rituals and remedies aimed at calming the mind and enhancing endurance, particularly in high-altitude regions where psychological stress is common.

However, while there is a substantial body of research on Rhodiola rosea for stress and anxiety, direct clinical studies on Rhodiola sacra are limited. The traditional use is thus the primary justification for its application in supporting worry or anxiety, rather than robust scientific validation. Some preclinical studies suggest potential adaptogenic and anxiolytic properties due to its content of salidroside and other bioactive compounds, but human clinical data specific to worry or anxiety are lacking. Therefore, the evidence supporting its use for worry is primarily traditional, and the strength of the supporting evidence is modest.

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