Relationship: Wounds and Sores and manganese

Evidence supporting the use of: Manganese
For the health condition: Wounds and Sores

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Synopsis
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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Manganese is an essential trace mineral involved in several biological processes, including the synthesis of connective tissue and wound healing. Scientifically, manganese serves as a cofactor for enzymes such as superoxide dismutase (MnSOD), which is important for protecting cells from oxidative damage during the inflammatory phase of wound healing. It also contributes to the formation of collagen, a key structural protein necessary for tissue repair. Animal studies have shown that manganese deficiency impairs collagen production and delays wound healing. Some in vitro studies also suggest that manganese supplementation can enhance fibroblast proliferation and improve the quality of new tissue formation.

However, direct clinical evidence in humans regarding the efficacy of manganese supplementation specifically for treating wounds and sores is limited. Most human studies focus on general nutritional support in wound care, where manganese is included as part of a broader micronutrient supplementation strategy rather than as a standalone treatment. Therefore, while there is mechanistic and preclinical support for manganese’s role in wound healing, robust clinical trials are lacking. Its use is justified scientifically based on its biological role, but the strength of direct clinical evidence is modest, warranting a score of 2 out of 5.

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3-Phenyllactic Acid
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Other health conditions supported by manganese

Diabetes
Osteoporosis
Wounds and Sores

Products containing manganese

Health Concerns

Brands

Evidence supporting the use of: Manganese
For the health condition: Wounds and Sores

Table of Contents

Synopsis

Other ingredients used for Wounds and Sores

Other health conditions supported by manganese

Products containing manganese

Health Concerns

Brands

Evidence supporting the use of: ManganeseFor the health condition: Wounds and Sores

Table of Contents

Synopsis

Other ingredients used for Wounds and Sores

Other health conditions supported by manganese

Products containing manganese

Evidence supporting the use of: Manganese
For the health condition: Wounds and Sores