Evidence supporting the use of: Astaxanthin
For the health condition: Wrinkles

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Astaxanthin, a carotenoid pigment found in microalgae, salmon, and other seafood, has garnered attention for its potential role in skin health, particularly in reducing wrinkles and improving skin elasticity. Several scientific studies, including randomized, double-blind, placebo-controlled trials, have explored astaxanthin's effects on skin aging markers. The primary mechanisms proposed include its potent antioxidant activity, which helps protect skin cells from oxidative stress induced by UV radiation—a major contributor to wrinkle formation. In both animal and human studies, oral supplementation and topical application of astaxanthin have shown improvements in skin moisture, elasticity, and reduced appearance of fine lines and wrinkles. For example, a 2012 study by Tominaga et al. demonstrated that daily oral and topical astaxanthin for 8 weeks led to statistically significant reductions in wrinkles and age spots in middle-aged women compared to placebo. However, sample sizes in these studies are often small, and longer-term studies are limited. Despite this, the available scientific literature provides moderate-quality evidence supporting astaxanthin's use for wrinkle reduction, primarily due to its antioxidant properties and its ability to improve skin texture and appearance. More large-scale and long-term clinical trials are needed to fully establish efficacy and determine optimal dosages.

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