Evidence supporting the use of: Blueberry
For the health condition: Wrinkles

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Blueberries are often promoted for skin health and anti-aging benefits, including the reduction of wrinkles. The justification for their use in this context is primarily scientific, though the evidence is limited and mostly preclinical. Blueberries are rich in antioxidants, especially anthocyanins, vitamin C, and polyphenols, which are believed to combat oxidative stress—a key factor in skin aging and wrinkle formation. Several in vitro and animal studies have shown that blueberry extracts can reduce markers of oxidative damage, protect collagen and elastin fibers, and enhance skin barrier function. For example, research published in the journal Oxidative Medicine and Cellular Longevity (2017) demonstrated that topical application of blueberry extract improved skin hydration and reduced wrinkle depth in mice exposed to UV radiation. However, well-designed human clinical trials evaluating blueberries or their extracts specifically for wrinkle prevention or treatment are lacking. Most human studies focus on overall skin health, with indirect implications for wrinkle formation. While the antioxidant properties of blueberries are well-established, direct clinical evidence supporting their use for treating wrinkles in humans is currently limited. Therefore, while there is a plausible scientific basis and some preliminary evidence, the strength of evidence is moderate at best.

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