Ferulic acid and its derivatives are increasingly used in dermatology and cosmeceuticals for their potential to support and treat wrinkles, and there is moderate scientific evidence to support their efficacy. Ferulic acid is a plant-derived phenolic compound known for its potent antioxidant properties. Several in vitro and in vivo studies have demonstrated that ferulic acid can neutralize free radicals and protect skin from oxidative stress, which is a significant factor in skin aging and wrinkle formation (Pinnell et al., 2005). Additionally, when combined with other antioxidants, such as vitamins C and E, ferulic acid has been shown to stabilize these compounds and increase their photoprotective effects, reducing UV-induced skin damage that accelerates wrinkle formation.

Clinical studies are limited but promising. For example, topical formulations containing ferulic acid derivatives have shown improvements in skin appearance, elasticity, and reduction of fine lines in some trials. However, most evidence comes from small-scale studies or studies where ferulic acid is used as part of a combination of antioxidants, making it difficult to isolate its specific effects. Overall, the scientific literature supports the use of ferulic acid derivatives for wrinkle prevention and treatment, primarily due to their antioxidant and photoprotective properties, but more large-scale, independent clinical trials are needed to fully validate these effects.