Evidence supporting the use of: Grape
For the health condition: Wrinkles
Synopsis
Source of validity: Scientific
Rating (out of 5): 3
Grapes, particularly their seeds and skins, contain high levels of polyphenols, including resveratrol, proanthocyanidins, and other antioxidants. Scientific studies have demonstrated that these compounds can help protect the skin from oxidative stress and UV-induced damage, two significant contributors to skin aging and wrinkle formation. Topical application or oral supplementation of grape-derived extracts has shown promising anti-aging effects in both in vitro and in vivo studies. For example, resveratrol has been found to improve the appearance of fine lines and wrinkles by stimulating collagen production and reducing inflammation in the skin. Grape seed extract, rich in proanthocyanidins, has demonstrated the ability to scavenge free radicals and protect the skin’s structural integrity, further contributing to its potential in wrinkle prevention and treatment.
However, while laboratory and animal studies are supportive, robust clinical trials on humans are somewhat limited. Some small human studies and cosmetic product trials have reported improvements in skin elasticity and reduction in wrinkle depth after using grape-derived ingredients, but larger-scale, long-term studies are needed to confirm these effects. Overall, the use of grape extracts for supporting or treating wrinkles is supported by a moderate level of scientific evidence, primarily based on their antioxidant and anti-inflammatory properties, but more clinical validation is warranted for definitive claims.
Other ingredients used for Wrinkles
Aloe veraanthocyanins
apricot
ascorbyl palmitate
astaxanthin
beta-carotene
blueberry
collagen
cryptoxanthin
d-alpha tocopherol
gelatin
genistein
grape
green tea
hyaluronic acid
L-carnosine
lycopene
Matcha
mixed carotenoids
resveratrol
silicon
Almond fruit
Urolithin A
vitamin A
vitamin C
β-nicotinamide mononucleotide (NMN)
Neem tree
ferulic acid
equol (proprietary)
avocado
Alpha hydroxy acids
alpha-lipoic acid
argan nut oil
Centella triterpenes
Carnosine
cocoa butter
cycloastragenol
fo-ti
flavanones
flavanols
flavones
Glycolic acid
Glycosylceramides
Gerovital H3
Glabridin
Haematococcus pluvialis
hydroxytyrosol
Idebenone
jojoba oil
Mulberroside A
Phytofluene
procyanidol
procyanidin
Phytoene
polymethoxylated flavones
silica
Ursolic Acid
Walnut
Other health conditions supported by grape
Alzheimer's DiseaseArteriosclerosis
Cancer (prevention)
Cardiovascular Disease
Cellulite
Chemotherapy (reducing side effects)
Cholesterol (high)
Cholesterol (low)
Circulation (poor)
Circulation (to the brain)
Colds (general)
Colds (prevention)
Colds (with fever)
Congestion (bronchial)
Congestion (lungs)
Constipation (children)
Convalescence
Cough (general)
Cough (spastic)
Debility
Dementia
Diabetes
Diabetic Retinopathy
Fatty Liver Disease
Free Radical Damage
Gastritis
Gingivitis
Hypertension
Inflammation
Memory and Brain Function
Phlebitis
Triglycerides (high)
Ulcers
Wrinkles
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Berberine Balance
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BergaVin™ 60 capsules
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Ceralin® Forte
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Cholesterol Support
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CurcumaSorb Mind
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Detox Antiox™
Integrative Therapeutics
Detoxication Factors
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Detoxification Support Packets
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DopaPlus
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EHB
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EssentiaGreens™
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Glucosamine + MSM Forte ™
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Hair Growth+
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Hair/Skin/Nails Ultra
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HTN Supreme™
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Juvenon Pro Cognitive
Klean Athlete
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Life's Essentials Plus
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Macular Support Formula
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Macular Support Formula
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MediClear Plus
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Optimized Curcumin With Neurophenol™
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PaleoCleanse Plus™
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PaleoCleanse Plus™
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PaleoCleanse Plus™ Detox Program
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PaleoCleanse Plus™Chocolate Detox Kit
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PaleoGreens®
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PaleoGreens®
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PaleoReds®
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PhytoBiome™
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PhytoMulti™ Multivitamin
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PhytoMulti With Iron
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PhytoMulti Without Iron
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PhytoMultivitamin
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Plant Protein Cleanse Plus™ 570g
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Polyphenol Nutrients
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Polyphenol Nutrients
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Primal Multi™
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Resveratrol Extra
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Resveratrol Extra
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Resveratrol Ultra HP 175mg
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Ultimate Antiox Full Spectrum
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Ultra Preventive
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Ultra Preventive
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Ultra Preventive ®-EZ Swallow
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Ultra Preventive® X
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Ultra Pure Pack
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Vessel Forte™
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Vision Support
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Wellness Essentials Active Daily Packs
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Wellness Essentials Healthy Balance Daily Packs
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Wellness Essentials Men's Vitality Daily Packs
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Wellness Essentials Women's Daily Packs
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Wellness Essentials Women's Prime Daily Packs
Pure Encapsulations
Women's Nutrients
