Evidence supporting the use of: Lycopene
For the health condition: Wrinkles
Synopsis
Source of validity: Scientific
Rating (out of 5): 2
Lycopene, a carotenoid found predominantly in tomatoes, has been studied for its antioxidant properties and potential skin benefits, particularly in relation to photoaging and wrinkles. Scientific evidence suggests that lycopene may help protect the skin from oxidative stress caused by ultraviolet (UV) radiation, which is a major contributor to the formation of wrinkles. Several small-scale clinical trials and in vitro studies have demonstrated that oral or topical lycopene supplementation can reduce markers of skin damage, improve skin texture, and decrease the depth of wrinkles. For example, a randomized controlled trial published in British Journal of Dermatology (2008) showed that subjects consuming a lycopene-rich tomato paste had less UV-induced erythema and improved skin texture compared to controls.
However, the strength of the evidence is still moderate. Most studies have relatively small sample sizes, short durations, and utilize combinations of antioxidants (such as lycopene with other carotenoids or vitamins), making it difficult to isolate lycopene’s effect. There is also a lack of large, long-term randomized controlled trials specifically targeting wrinkle reduction as a primary endpoint. Nonetheless, the available evidence supports a role for lycopene in skin photoprotection, which indirectly relates to wrinkle prevention and reduction. In summary, lycopene’s use for supporting or treating wrinkles is justified by moderate scientific evidence, primarily due to its antioxidant activity and protective effects against photoaging.
Other ingredients used for Wrinkles
Aloe veraanthocyanins
apricot
ascorbyl palmitate
astaxanthin
beta-carotene
blueberry
collagen
cryptoxanthin
d-alpha tocopherol
gelatin
genistein
grape
green tea
hyaluronic acid
L-carnosine
lycopene
Matcha
mixed carotenoids
resveratrol
silicon
Almond fruit
Urolithin A
vitamin A
vitamin C
β-nicotinamide mononucleotide (NMN)
Neem tree
ferulic acid
equol (proprietary)
avocado
Alpha hydroxy acids
alpha-lipoic acid
argan nut oil
Centella triterpenes
Carnosine
cocoa butter
cycloastragenol
fo-ti
flavanones
flavanols
flavones
Glycolic acid
Glycosylceramides
Gerovital H3
Glabridin
Haematococcus pluvialis
hydroxytyrosol
Idebenone
jojoba oil
Mulberroside A
Phytofluene
procyanidol
procyanidin
Phytoene
polymethoxylated flavones
silica
Ursolic Acid
Walnut
Other health conditions supported by lycopene
Alzheimer's DiseaseBenign Prostate Hyperplasia
Cancer (natural therapy for)
Cancer (prevention)
Cancer Treatment (reducing side effects)
Cardiovascular Disease
Cervical Dysplasia
Cholesterol (high)
Diabetes
Diabetic Retinopathy
Hypertension
Prostatitis
Triglycerides (high)
Wrinkles
Products containing lycopene
Vitabase
Active Man's Formula
Thorne
Advanced Nutrients Multivitamin
Pure Encapsulations
AntiOxidant Formula
Metagenics
CardioLux® HDL
Klean Athlete
Klean Multivitamin ™
Designs For Health
Lipotrienols RYR™
Pure Encapsulations
Lycopene 20 mg
Pure Encapsulations
Lycopene 20 mg
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Men's Multi 50+
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NeuroMood Pure Pack
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NutraGems® CoQ10 300
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O.N.E.™ Multivitamin
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O.N.E.™ Multivitamin
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O.N.E.™ Multivitamin
Metagenics
PhytoMulti™ Multivitamin
Metagenics
PhytoMulti With Iron
Metagenics
PhytoMulti Without Iron
Metagenics
PhytoMultivitamin
Pure Encapsulations
Polyphenol Nutrients
Douglas Laboratories
Prenatal
Pure Encapsulations
PreNatal Nutrients
Pure Encapsulations
PreNatal Nutrients
Designs For Health
Primal Multi™
Vitabase
Prostate Complex (Formerly Prostate Complete)
Vitabase
Prostate Support
Designs For Health
Prostate Supreme™
Designs For Health
Prostate Supreme™
Pure Encapsulations
SP Ultimate
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SP Ultimate
Metagenics
Testralin®
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Ultimate Antiox Full Spectrum
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Ultra Preventive
Douglas Laboratories
Ultra Preventive
Douglas Laboratories
Ultra Preventive ® 2 Daily
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Ultra Preventive 50+ -EZ Swallow
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Ultra Preventive ®-EZ Swallow
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Ultra Preventive One Daily
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Ultra Preventive® X
Metagenics
Ultra Prostagen Concentrated
Pure Encapsulations
UltraDetox 10-Day Pure Pack
Pure Encapsulations
UltraNutrient®
Pure Encapsulations
UltraNutrient®
Pure Encapsulations
UltraNutrient®
Pure Encapsulations
Vascular Relax
Pure Encapsulations
VisionPro Nutrients
Metagenics
Wellness Essentials Active Daily Packs
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Wellness Essentials Brain Health Daily Packs
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Wellness Essentials® Daily Packs
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Wellness Essentials Healthy Balance Daily Packs
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Wellness Essentials Men's Vitality Daily Packs
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Wellness Essentials Women's Daily Packs
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Wellness Essentials Women's Prime Daily Packs
Pure Encapsulations
Women's Nutrients
