Evidence supporting the use of: Silicon
For the health condition: Wrinkles

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Silicon, particularly in the form of orthosilicic acid or silica, is sometimes used in dietary supplements and topical formulations aimed at improving skin health, including the reduction of wrinkles. The rationale is that silicon is an essential trace element involved in the synthesis of collagen and glycosaminoglycans, both of which are critical components of the skin's extracellular matrix and are associated with skin elasticity and firmness. Several small clinical studies have indicated that oral supplementation with bioavailable forms of silicon (e.g., choline-stabilized orthosilicic acid) may lead to improvements in skin roughness and elasticity, and a reduction in the depth or appearance of wrinkles. For example, a randomized, double-blind, placebo-controlled study published in Archives of Dermatological Research (2005) showed that women who took a daily silicon supplement for 20 weeks had improved skin surface characteristics compared to placebo. However, the overall quality and size of the evidence base remain limited, with most studies having small sample sizes and short durations. Topical use of silicon in creams or patches (such as silicone gel sheets) is more established for scar management rather than wrinkle reduction, and evidence for direct anti-wrinkle effects is sparse. In summary, while there is some scientific basis and preliminary human data supporting the potential role of silicon in supporting skin structure and possibly reducing wrinkles, the evidence is not robust, and more large-scale, well-designed trials are needed.

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