Integrative Therapeutics NAC | Antioxidant & Liver Support

Integrative Therapeutics NAC delivers 600 mg of N-Acetyl L-Cysteine (NAC) per capsule — the acetylated precursor of the amino acid L-cysteine. NAC is valued for its ability to help replenish intracellular glutathione, which is vital in cellular antioxidant pathways. Glutathione is the body's principal endogenous antioxidant, and its synthesis is limited by the availability of cysteine — making NAC a critical precursor.

Easily absorbed, NAC supplementation enhances glutathione levels in the body, supporting the production of glutathione as an essential component of the body's cellular and liver detoxification pathways. Integrative Therapeutics NAC also supports healthy lung and respiratory function.

This formula is free from gluten and dairy, and contains no sugar, yeast-derived ingredients, wheat, corn, soy, artificial colors, flavors, or preservatives.

NAC is a membrane-permeable cysteine precursor that does not require active transport. After free NAC enters a cell, it is rapidly hydrolyzed to release cysteine, which feeds into the de novo synthesis of glutathione (GSH). GSH is synthesized intracellularly by the consecutive actions of γ-glutamylcysteine synthetase and GSH synthetase, and cysteine is usually the limiting precursor in this pathway.

Among glutathione's many established roles are antioxidant defense, detoxification of electrophilic compounds, modulation of redox-regulated signal transduction, regulation of immune responses, and support of cell proliferation. By replenishing GSH in depleted cells, NAC aids the body's natural detoxification and defense systems.

Beyond its glutathione precursor activity, research suggests NAC also functions through several additional mechanisms:

• Direct free radical scavenging: NAC interacts with reactive oxygen species (ROS) such as hydroxyl radicals and hydrogen peroxide through its sulfhydryl (thiol) group.
• Anti-inflammatory activity: Research suggests NAC may reduce levels of pro-inflammatory cytokines including TNF-α, IL-6, and IL-1β by suppressing the activity of nuclear factor kappa B (NF-κB).
• Mucolytic action: The thiol group cleaves disulfide bonds within mucus glycoproteins, thereby reducing mucus viscosity and supporting respiratory function.
• Heavy metal chelation: NAC is capable of binding transition metal ions and heavy metal ions such as cadmium, mercury, and lead through its thiol side chain, forming complexes that may be excreted from the body.

Integrative Therapeutics NAC may be appropriate for adults looking for targeted support in several key health areas:

• Antioxidant defense: Individuals seeking to support their body's glutathione levels, particularly those concerned about oxidative stress from environmental exposures, lifestyle factors, or aging.
• Liver and detoxification support: Those looking to promote healthy liver detoxification pathways. NAC is a precursor to hepatic glutathione — the liver's primary endogenous antioxidant and detoxification agent.
• Immune system support: Research suggests NAC supports immune function by replenishing intracellular glutathione and modulating inflammatory cytokines.
• Respiratory health: NAC supports healthy lung and respiratory function through its mucolytic properties.
• Seasonal immune challenges: Studies suggest NAC may help reduce the severity of influenza-like illness symptoms.

This product is free from gluten, dairy, sugar, wheat, corn, soy, and artificial additives, making it suitable for individuals with common dietary sensitivities.

Take 1 capsule once or twice daily, or as recommended by your healthcare professional.

Each bottle contains 60 capsules. At the suggested use of one capsule daily, this provides a two-month supply; at two capsules daily, a one-month supply.