Designs for Health NeuroMag | Brain Magnesium Support

Designs for Health NeuroMag™ is a specialized Magnesium supplement built around one goal: delivering Magnesium directly to the brain. Unlike conventional Magnesium forms that primarily support general mineral status, NeuroMag uses the patented mineral Magtein® — Magnesium chelated to threonic acid (Magnesium L-threonate) — a highly bioavailable form that has the potential to cross the blood-brain barrier.

Magnesium is a cofactor in more than 300 enzyme systems that regulate diverse biochemical reactions in the body, yet emerging evidence confirms that nearly two-thirds of the population in the western world is not achieving the recommended daily allowance for Magnesium. This widespread shortfall is especially concerning for the brain, where Magnesium levels naturally decline with age. Research demonstrates that elevating brain Magnesium content through supplementation with Magnesium L-threonate may be a useful strategy to support cognitive abilities and healthy memory.

NeuroMag is vegan, vegetarian-friendly, non-GMO, and made without gluten, dairy, or soy — making it accessible for a wide range of dietary needs.

Not all forms of Magnesium are created equal when it comes to brain health. While forms like Magnesium citrate and Magnesium oxide support general Magnesium status, Magnesium L-threonate has gained attention for its potential cognitive benefits, attributed to its ability to cross the blood-brain barrier. This unique characteristic is central to the design of NeuroMag.

Magnesium is critical to brain function, serving as a voltage-dependent blocker of NMDA receptors, a regulator of synaptic plasticity, and a neuroprotective agent against excitotoxicity and neuroinflammation. Brain Magnesium levels decline with age and are reduced in patients with Alzheimer's disease. Research suggests that elevating brain Mg²⁺ via Magnesium L-threonate may help reverse synaptic loss and support cognitive function, with supporting human RCT evidence.

Magnesium also plays a role in neurotransmitter balance. It is an essential mineral cofactor in dopamine synthesis (tyrosine hydroxylase) and a physiological blocker of NMDA glutamate receptor channels, supporting the delicate balance between excitatory and inhibitory neurotransmitter activity. Additionally, Magnesium modulates the HPA axis, supports GABA receptor function, and reduces neuroinflammation — all relevant pathways for brain health and the gut-brain connection.

NeuroMag is formulated for adults seeking targeted brain and cognitive support, particularly those concerned with age-related changes in memory and mental clarity. As we age, Magnesium absorption and retention can decrease, leading to deficiency and health consequences. Older people are more susceptible to Magnesium deficiency due to factors like decreased absorption from food, increased medication use, and potential dietary restrictions.

This supplement may be particularly relevant for individuals experiencing occasional brain fog, those looking to support healthy cognitive aging, or adults who want a form of Magnesium specifically researched for brain penetration. Research suggests that low Magnesium is linked to reduced cognitive function, neuroinflammation, and impaired stress responses.

It is estimated that between 56 and 68% of Americans do not obtain enough Magnesium in their diet on a daily basis to meet the recommended daily allowance. Men older than 70 and teenage girls are most likely to have low intakes. NeuroMag offers a targeted solution for those looking to address potential brain Magnesium shortfalls with a clinically studied form.

Take 3 capsules per day or as directed by your health-care practitioner.

Each bottle contains 90 capsules, providing a full 30-day supply at the recommended serving size. Each 3-capsule serving delivers 145 mg of elemental Magnesium from 2 grams of Magtein® Magnesium L-threonate.