Digestive Enzyme | Complete Guide to Enzyme Support
Learn how Digestive Enzyme supplements with Pancreatin, Amylase, and Lipase support digestion, nutrient absorption, and food sensitivity. Science-backed guide.
What Is a Digestive Enzyme and Why Does It Matter?
Each day the body produces several thousands of enzymes. The body uses enzymes for all its chemical actions and reactions. A Digestive Enzyme is produced in the salivary glands of the mouth and in the stomach, pancreas, and small intestine. These enzymes are responsible for the digestion of nutrients as well as their absorption, transportation, metabolization, and elimination.
The body uses three main kinds of enzymes in the digestive process: Amylase enzymes break down starches and carbohydrates, protease enzymes break down proteins, and Lipase aids in fat digestion. Because enzymes are extremely sensitive to heat, many are harmed by modern food-processing methods like microwaving and pasteurization, which can render them ineffective.
When Digestive Enzyme activity is insufficient β whether due to genetics, illness, surgery, aging, or other factors β the body may struggle to properly break down food. This can lead to malabsorption, uncomfortable gastrointestinal symptoms, and difficulty obtaining essential nutrients from the diet.
How This Digestive Enzyme Formula Supports Digestion
This Digestive Enzyme formula contains all three principal groups of digestive enzymes β Amylase, protease, and Lipase β working together to promote the complete digestion of carbohydrates, proteins, and fats. It features a 4:1 extract of Pancreatin that is equivalent to 1,300 mg of Pancreatin, providing a concentrated source of these essential enzymes.
Beyond the three primary enzyme groups, this formula also contains esterase, peptidase, nuclease, elastaste, collagenase, trypsin, and chymotrypsin. Trypsin and chymotrypsin are pancreatic endoproteases that boost the breakdown of dietary proteins into smaller, more easily absorbed particles. Together, these enzymes work synergistically to promote the complete digestion of proteins, carbohydrates, and lipids, supporting optimal nutrient absorption in the small intestine.
This product is gluten free.
Key ingredients

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Who May Benefit from a Digestive Enzyme Supplement
This Digestive Enzyme formula may be helpful for individuals who experience digestive discomfort after meals, including symptoms such as bloating, gas, fullness, or irregular bowel patterns. Anyone who feels that their body may not be adequately breaking down the foods they eat β particularly meals high in fats, starches, or proteins β may find enzyme supplementation supportive.
An inadequate production of, or an excessive requirement for, pancreatic enzymes can occur for a variety of reasons including genetics, illness, surgery, injury, exercise, aging, and exposure to toxins. Individuals who frequently consume processed or cooked foods may also want to consider supplementation, as modern food-processing methods like microwaving and pasteurization can harm the enzymes naturally present in foods.
People with food sensitivities related to carbohydrate or fat maldigestion may also find this formula beneficial. Research suggests that Amylase supplementation may help reduce bloating and gas related to carbohydrate maldigestion, while Lipase supports improved fat digestion and may help reduce gastrointestinal symptoms in those with insufficient enzyme activity.
How to Take This Digestive Enzyme
The recommended serving size is 3 capsules. Each bottle contains 50 capsules. For best results, take with meals to support the digestive process as the body breaks down carbohydrates, proteins, and fats.
Because Digestive Enzyme activity occurs primarily within the gastrointestinal tract during the digestive process, timing supplementation with food intake helps ensure the enzymes are available when they are most needed.
Written by Greg Howlett
Frequently asked questions
What are the three main types of digestive enzymes in this formula?
This formula contains all three principal groups of digestive enzymes: Amylase, which breaks down starches and carbohydrates; protease, which breaks down proteins; and Lipase, which aids in fat digestion. It also contains additional enzymes including esterase, peptidase, nuclease, elastaste, collagenase, trypsin, and chymotrypsin.
What does the 4X Pancreatin concentration mean?
The 4:1 extract means the Pancreatin is concentrated at four times the standard potency. Each serving contains 325 mg of Pancreatin (4X), which is equivalent to 1,300 mg of standard Pancreatin. This concentration provides a robust level of Amylase, protease, and Lipase enzymes to support the digestive process.
Why is porcine-sourced Pancreatin used in this product?
Porcine pancreatic juice is closest to that of humans, with high proportions of Lipase and alpha-Amylase compared to other mammals. This makes porcine Pancreatin well-suited for supplementing human Digestive Enzyme activity. The porcine pancreas has been the predominant source for pancreatic enzyme preparations for over a century.
Is this Digestive Enzyme product gluten free?
Yes, this Digestive Enzyme formula is gluten free.
Why might I need a Digestive Enzyme supplement?
The body's enzyme production can be affected by many factors including genetics, illness, surgery, aging, exercise, and toxin exposure. Additionally, enzymes are extremely sensitive to heat, and modern food-processing methods like microwaving and pasteurization can render them ineffective. Supplemental digestive enzymes may help support the breakdown and absorption of nutrients from your meals.
How do digestive enzymes support nutrient absorption?
Digestive enzymes are responsible for digestion of nutrients as well as their absorption, transportation, metabolization, and elimination. Research suggests that Pancreatin, the multi-enzyme complex in this formula, supports the complete digestion of proteins, carbohydrates, and lipids, promoting optimal nutrient absorption in the small intestine. Lipase in particular is also required for the absorption of fat-soluble vitamins A, D, E, and K.
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