Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Vitamin B12 (cobalamin) has a modest scientific basis for use in supporting mental health, including anxiety, but it is not a primary or direct treatment for anxiety disorders. B12 is essential for neurological function, DNA synthesis, and the production of neurotransmitters such as serotonin and dopamine, which are involved in mood regulation. Deficiency in vitamin B12 can lead to neurological symptoms, including cognitive disturbances, mood changes, and in some cases, increased anxiety or depressive symptoms. Some observational studies have found associations between low B12 levels and higher prevalence of mood and anxiety disorders, particularly in older adults and vegetarians who are at higher risk for deficiency.

However, well-controlled clinical trials directly investigating B12 supplementation as a treatment for anxiety in non-deficient individuals are lacking. The available evidence suggests that correcting a deficiency can improve mood and reduce anxiety-like symptoms, but supplementation in those with normal levels does not appear to have anxiolytic effects. Therefore, the role of B12 in anxiety management is primarily as a supportive measure in cases where deficiency is present, rather than as a general remedy for anxiety. Clinical guidelines recommend screening for B12 deficiency when neuropsychiatric symptoms are unexplained. In summary, B12 is scientifically justified in select cases of anxiety related to deficiency, but not as a universal treatment for anxiety.

More about vitamin B12
More about Anxiety

Other ingredients used for Anxiety

Other health conditions supported by vitamin B12

Products containing vitamin B12

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Vitabase Active Man's Formula
Vitabase Active Woman's Multi
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Pure Encapsulations Women's Nutrients
Pure Encapsulations Women's Nutrients
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