Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Niacinamide (vitamin B3) is a form of vitamin B3 distinct from niacin (nicotinic acid). While niacin is well established for its role in improving blood lipid profiles and supporting cardiovascular health, niacinamide has less direct evidence for supporting the arteries or cardiovascular system specifically. Unlike niacin, niacinamide does not significantly lower cholesterol or triglyceride levels, and it lacks the vasodilatory (blood vessel-widening) effects of niacin. However, niacinamide does show some scientific support for vascular health through its anti-inflammatory and endothelial-protective properties, which may indirectly benefit artery function.

Some studies suggest that niacinamide may help to reduce oxidative stress and inflammation, both of which are linked to the development of atherosclerosis (hardening and narrowing of the arteries). For example, preclinical studies have shown that niacinamide can protect endothelial cells (the lining of blood vessels) from injury and dysfunction. However, robust clinical trials directly demonstrating that niacinamide improves arterial health or prevents arterial disease in humans are lacking. Most cardiovascular guidelines and reviews emphasize niacin, not niacinamide, for lipid modification and arterial health.

In summary, while there is some scientific rationale and limited experimental evidence suggesting niacinamide might support arterial health via indirect mechanisms, its benefits for this body system are not as well validated as those of niacin. Thus, the overall evidence strength is moderate (3/5).

More about niacinamide (vitamin B3)
More about Arteries

Other ingredients that support Arteries

Other body systems supported by niacinamide (vitamin B3)

Products containing niacinamide (vitamin B3)

Designs For Health Acnutrol™ capsules
Vitabase Active Man's Formula
Vitabase Active Woman's Multi
Designs For Health ArthroSoothe™
Metagenics Axis Endo™ Mango
Vitabase B-Complex 100 mg Sustained Release
Thorne B-Complex #12
Thorne B-Complex #6
Designs For Health B-Supreme
Thorne Basic B Complex
Thorne Basic Nutrients 2/Day Multivitamin
Thorne Basic Prenatal Multivitamin
Metagenics Bone Builder Active
Metagenics Ceralin® Forte
Metagenics Clear Change 10-Day Detox Program with UltraClear Plus Berry
Metagenics Clear Change 10-Day Detox Program with UltraClear Plus pH
Metagenics Clear Change 10-Day Detox Program with UltraClear Plus pH Pineapple Banana
Metagenics Clear Change 10-Day Detox Program with UltraClear Plus Pineapple Banana
Metagenics Clear Change 10-Day Detox Program with UltraClear Plus Vanilla
Metagenics Clear Change 10-Day Detox Program with UltraClear RENEW Berry
Metagenics Clear Change 10-Day Detox Program with UltraClear RENEW Chai
Metagenics Clear Change 10-Day Detox Program with UltraClear RENEW Vanilla
Metagenics Clear Change 28-Day Detox Program with UltraClear Plus Berry
Metagenics Clear Change 28-Day Detox Program with UltraClear Plus pH Pineapple Banana
Metagenics Clear Change 28-Day Detox Program with UltraClear Plus pH Vanilla
Metagenics Clear Change 28-Day Detox Program with UltraClear Plus Pineapple Banana
Metagenics Clear Change 28-Day Detox Program with UltraClear Plus Vanilla
Metagenics Clear Change 28-Day Detox Program with UltraClear RENEW Berry
Metagenics Clear Change 28-Day Detox Program with UltraClear RENEW Chai
Metagenics Clear Change 28-Day Detox Program with UltraClear RENEW Vanilla
Integrative Therapeutics Clinical Nutrients HP
Designs For Health CraveArrest™
Thorne Craving and Stress Support Relora Plus
Metagenics Echinacea Synergy
Metagenics Endura® Lemonade
Metagenics GI Sustain™ Powder
Metagenics GlutaClear®
Integrative Therapeutics Glycemic Manager
Pure Encapsulations Hist Reset
Metagenics ImmuCore
Integrative Therapeutics K-PAX MitoNutrients
Metagenics Ketogenic Shake Chocolate
Metagenics Ketogenic Shake Vanilla
Klean Athlete Klean B-Complex
Pure Encapsulations Liquid B-Complex
Douglas Laboratories Liquid Multivitamin
Pure Encapsulations LiquiNutrients
Thorne MediClear Plus
Thorne Men's Multi 50+
Metagenics MetaGlycemX™
Metagenics MetaGlycemX
Metagenics MetaKids Multi Soft Chew Grape
Metagenics MetaKids Nutrition Powder Chocolate
Metagenics MetaKids Nutrition Powder Vanilla
Designs For Health Mitochondrial NRG™
Metagenics MitoVive
Metagenics Multigenics®
Metagenics Multigenics Chewable Orange
Designs For Health Niacin CRT™
Thorne Niacinamide
Douglas Laboratories Niacinamide 500 mg
Designs For Health OcuForce™
Integrative Therapeutics Osteoprime Ultra
Designs For Health PaleoCleanse Plus™
Designs For Health PaleoCleanse Plus™
Designs For Health PaleoCleanse Plus™ Detox Program
Designs For Health PaleoCleanse Plus™Chocolate Detox Kit
Designs For Health Plant Protein Cleanse
Designs For Health Plant Protein Cleanse Plus™ 570g
Designs For Health Plant Protein Meal
Designs For Health Plant Protein Meal Plus
Designs For Health Plant Protein Meal
Douglas Laboratories Prenatal
Designs For Health Prenatal Pro™
Pure Encapsulations PurePals
Pure Encapsulations PurePals with Iron
Pure Encapsulations PureResponse™ Multivitamin
Douglas Laboratories Relora ®-Plex
Pure Encapsulations SeroPlus
Thorne Stress B-Complex
Douglas Laboratories Stress-B-Plus ™
Designs For Health StressArrest™
Vitabase Super Stress Formula
Metagenics Thyrosol
Metagenics Ultra Glucose Control Vanilla
Metagenics Ultra Potent-C 1000
Metagenics Ultra Potent-C 500
Metagenics Ultra Potent-C Chewable
Douglas Laboratories Ultra Preventive One Daily
Douglas Laboratories Ultra Protein Green
Metagenics UltraClear Detox Powder
Metagenics UltraClear Plus® Detox Powder
Metagenics UltraClear Plus Detox Powder Berry
Metagenics UltraClear Plus Detox Powder Pineapple/Banana
Metagenics UltraClear Plus pH Detox Powder Pineapple/Banana
Metagenics UltraClear Plus pH Detox Powder Vanilla
Metagenics UltraClear RENEW Detox Powder Berry
Metagenics UltraClear RENEW Detox Powder Chai
Metagenics UltraClear RENEW Detox Powder Vanilla
Pure Encapsulations UltraDetox 10-Day Pure Pack
Metagenics UltraMeal® Daily Support Dutch Chocolate
Metagenics UltraMeal Daily Support Mixed Berry