Relationship: Arteries and niacinamide (vitamin B3)

Evidence supporting the use of: Niacinamide (vitamin B3)
For the body system: Arteries

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Niacinamide (vitamin B3) is a form of vitamin B3 distinct from niacin (nicotinic acid). While niacin is well established for its role in improving blood lipid profiles and supporting cardiovascular health, niacinamide has less direct evidence for supporting the arteries or cardiovascular system specifically. Unlike niacin, niacinamide does not significantly lower cholesterol or triglyceride levels, and it lacks the vasodilatory (blood vessel-widening) effects of niacin. However, niacinamide does show some scientific support for vascular health through its anti-inflammatory and endothelial-protective properties, which may indirectly benefit artery function.

Some studies suggest that niacinamide may help to reduce oxidative stress and inflammation, both of which are linked to the development of atherosclerosis (hardening and narrowing of the arteries). For example, preclinical studies have shown that niacinamide can protect endothelial cells (the lining of blood vessels) from injury and dysfunction. However, robust clinical trials directly demonstrating that niacinamide improves arterial health or prevents arterial disease in humans are lacking. Most cardiovascular guidelines and reviews emphasize niacin, not niacinamide, for lipid modification and arterial health.

In summary, while there is some scientific rationale and limited experimental evidence suggesting niacinamide might support arterial health via indirect mechanisms, its benefits for this body system are not as well validated as those of niacin. Thus, the overall evidence strength is moderate (3/5).

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Other body systems supported by Niacinamide (vitamin B3)

Arteries
Blood
Brain
Circulatory System
Hepatic System
Immune System
Liver
Mitochondria
Nerves
Skin

Products containing Niacinamide (vitamin B3)

Health Concerns

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Evidence supporting the use of: Niacinamide (vitamin B3)
For the body system: Arteries

Table of Contents

Synopsis

Other ingredients that support Arteries

Other body systems supported by Niacinamide (vitamin B3)

Products containing Niacinamide (vitamin B3)

Health Concerns

Brands

Evidence supporting the use of: Niacinamide (vitamin B3)For the body system: Arteries

Table of Contents

Synopsis

Other ingredients that support Arteries

Other body systems supported by Niacinamide (vitamin B3)

Products containing Niacinamide (vitamin B3)

Evidence supporting the use of: Niacinamide (vitamin B3)
For the body system: Arteries