Relationship: Arthritis and vitamin B6

Evidence supporting the use of: Vitamin B6
For the health condition: Arthritis

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Synopsis
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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Vitamin B6 (pyridoxine) has been investigated for its potential role in supporting or treating arthritis, particularly rheumatoid arthritis (RA). Some studies have found that people with RA tend to have lower levels of vitamin B6, possibly due to increased metabolic needs or inflammation-induced depletion. Vitamin B6 is essential for normal immune function and the synthesis of neurotransmitters, and it is involved in modulating inflammatory pathways. Several small clinical trials and observational studies have examined the effects of vitamin B6 supplementation in people with arthritis. For example, a study published in "The Journal of Rheumatology" (2005) found that supplementation with high-dose vitamin B6 (50 mg/day) reduced levels of certain inflammatory markers in RA patients. However, the improvements in clinical symptoms such as pain and joint swelling were limited or inconsistent across studies.

There is not enough high-quality, large-scale clinical evidence to firmly establish vitamin B6 as a treatment for arthritis symptoms themselves. Most guidelines do not recommend vitamin B6 supplementation specifically for arthritis, except in cases of confirmed deficiency. The available evidence suggests a possible adjunctive role in managing inflammation, but not as a standalone therapy. Therefore, while there is some scientific basis for its use, the strength of evidence is limited and more research is needed.

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Other ingredients used for Arthritis

adrenal cortex
alfalfa
algal oil
allspice
aloe vera
alpha-linolenic acid (ALA)
alpha-pinene
amino acids
anthocyanins
ashwagandha
astaxanthin
bamboo
barberry
basil
berry flavor
beta caryophyllene
Beta-Glucan
black cumin
black currant
black garlic
black pepper
sesame
black tea
blackberry
blueberry
borage oil
boron
Indian frankincense
bovine
bovine gelatin
broccoli
bromelain
burdock
calamari oil
cannabis sativa oil
capsaicinoids
carrot
cartilage
cat's claw
caterpillar mushroom
celery
cherry
chondroitin
chymotrypsin
cinnamon
citrus oil
clove
collagen
collard
conjugated linoleic acid (CLA)
copper
cordyceps
cowage seed
cryptoxanthin
turmeric
curcumin
devil's claw
DHA (docosahexaeonic acid)
DPA (docosapentaenoic acid)
EPA (eicosapentaenoic acid)
epigallocatechin gallate (EGCG)
evening primrose oil
fish oil
fish protein
flavonols
flaxseed
gamma linolenic acid (GLA)
gamma tocopherol
gelatin
genistein
ginger
ginseng
glucosamine
gooseberry
gotu kola
green lipped mussel
green tea
guggul
heartwood
hemp oil
horsetail
hyaluronic acid
Indian tinospora
knotweed
kale
krill oil
kudzu
luteolin
mackerel
magnesium
marine lipid
methylsulfonylmethane (MSM)
microbial enzymes (proprietary)
microcrystalline hydroxyapatite concentrate (MCHC)
moringa
mustard seed
myristoleate
n-acetyl-glucosamine
n-acetyl-cysteine (NAC)
nettle
niacinamide (vitamin B3)
spruce
oleanolic acid
oleic acid
olive
omega-3 fatty acids
orange
oregon grape
papain
phellodendron amurense
phenolic acids
phospholipids
phytocannabinoids
pine bark
pineapple
plantain
pollen
pomegranate
pregnenolone
pumpkin
quercetin
raspberry
redcurrant
reishi mushroom
resveratrol
rhizome
rose hips
rosemary
sardines
schizonepeta
scrophularia root
serratiopeptidase
black ginger
specialized pro-resolving mediators (SPMs)
sphaeranthus indicus
spinach
spirulina
strawberry
strontium
thyme
triphala
ubiquinol
vitamin B
vitamin B6
vitamin C
vitamin D
vitamin D3
vitamin E
seaweed
water
watercress
wheat grass
mulberry
white willow
wild yam
zinc
sarsaparilla
yellow root
suma
squawvine
jiaogulan
typhonium
xanthium (cockleburs)
gastrodia
papaya
shen-chu
capsicum
mugwort
alpinia galangal
clerodendrum indicum
punarnava
commiphora
smilax
tinospora cordifolia
blackboard tree
caesalpinia crista
rubia cordifolia
bee pollen
peony
lingzhi
lingusticum wallichii
buckthorn
morus
lemongrass
myrrh
root tuber
ferulic acid
silk tree
chrysanthemum
haliotis
juniper berries
solomon's seal
amber
dioscorea
dodder
ganoderma
sweetgums
morinda
zanthoxylum
birch
royal jelly
guelder rose
polyphenols
trace minerals
purslane
fulvic acid
yucca
barrenwort
wintergreen
menthol oil
gentiana macrophylla
noni
biota seed
goji berry
abies spectabilis
herbal blend (proprietary)
algae
indigo leaves
AMP-activated protein kinase (AMPK)
enzymes blend (proprietary)
cayenne pepper
soursop
geranium
clematis
3-(4-hydroxy-3-methoxyphenyl)prop-2-enoic acid
Ash
Aralia
Avens
akebia
Apple Cider Vinegar
Aminomonosaccharide
Animal Tissue
Antler
Alpha-Humulene
Ardisia
Angelica
Apigenin
Allicin
Achyranthes
Anamu
Abrus
Albizia
Aconite
Ajuga
Aucubin
Andrographolide
Avocado
Anserina
Ascophyllum nodosum
American Liverleaf
Anemone
Acacetin
Alpha-Lipoic Acid
Astragaloside
anthocyanidins
Andrographis
Ampelopsin
Actaea spicata
Asteracea
Avenacosides
Acetylsalicylic acid
Arjunic Acid
Aspen
Ant
Abalone
Abuta
Allium tuberosum
Amor seco
Arani
Arisaema
Alantolactone
Apocynin
Astragalin
Atractylone
Bee Propolis
Betony
Black Seed
Bermuda Grass
Baikal Skullcap
Bidens pilosa
Broussonetia
Bulnesia sarmientoi
bergenin
Blubber oil
Blepharis
Balsam
Bishop's Weed
Boswellic Acid
Bayleaf
Butea monosperma
Black galingale
Barleria
Big Quaking Grass
Bugbane
Bone Marrow
Baicalein
Bee hive
Bovine Protein
Basidiomycota
berry
Bogbean
Boswellia
Black Poplar
Banyan
Black willow
Boxwood
Bur-Reed
Bioflavonoids
Barbasco
Bone Protein
Bee products
Barbary matrimony vine
Black Nightshade
Bombax
Borassus Palm
Borassus aethiopum
Babassu
Bacteria
Borage
bovine cartilage / glycosaminoglycan
Black root
Bupleurum
Bittersweet
benzyl isothiocyanate
Baicalin
Bassia scoparia
Burning Bush
Bee venom
Bergenia
Boerhavia diffusa
Borneol
Camellia sinensis
Centella triterpenes
Chinese Silkvine
Curry leaf
Caryophyllene
Cinnamomum
Chinese Mountain Ant
Crustaceans
Clerodendrum trichotomum
Camelina Oil
Cod Liver Oil
Cortisol
Cnidium
Clerodendrum phlomidis
Cactus
Capillary Artemisia
Cyanidin
Chinese Fleeceflower
Curcuminoid
Citrus
Capsaicin
Chinese Pond Turtle
Chinese Raisintree
Chlorophytum
Chuchuhuasi
Cowherb
Cruciferous
Curcumen
Centella asiatica
Cetylated Fatty Acids
Cedar
Corktree
Curcuma
Calanus finmarchicus
C-Phycocyanin
Cabbage
Crinum latifolium
Cannabidiol
Cinnamaldehyde
Cytokines
Corallina officinalis
Carthamus
Celastrus
Copaiba Oil
Clerodendrum indicum
Currant
Cannabichromene
Cannabigerol
Dimorphandra mollis
Docosahexaenoic Acid
Dodeca-2E, 4E-Dienoic Acid Isobutylamide
Daphne
Devil's Club
Dihomo-gamma-linolenic acid
Dwarf Nettle
Dulse
Diterpenes
Dimethyl sulfoxide (DMSO)
Dipsacus
European Elder
Erythropalum scandens
Eupolyphaga sinensis
Erodium cicutarium
Eclipta
Elk antler
Emblicanin
Emu Oil
Enzyme Blend
Eicosapentaenoic Acid
Essential Oil Blend
Elephant's Head
Evening Primrose Oil
European-Five Finger Grass
Echium
Eugenol
Ecklonia
Flavonoids
Flavonones
Glycosaminoglycans
Lotus
Mustard
Spikenard
Snakeroot (unspecified)
Sandalwood
Sumac
walnut
Zucchini

Other health conditions supported by vitamin B6

Alcoholism
Amenorrhea
Anemia
Anxiety
Anxiety Disorders
Anger (excessive)
Arthritis
Attention Deficit Disorder
Autism
Bell's Palsy
Burning Feet or Hands
Carpal Tunnel Syndrome
Chemotherapy (reducing side effects)
Depression
Diabetes
Dysmenorrhea
Emotional Sensitivity
Energy (lack of)
Epilepsy
Fatigue
Hair (loss or thinning)
Hair Care (general)
Hangover
Hashimoto's Disease
Hiccups
Hot Flashes
Infertility
Inflammation
Insomnia
Irritability
Kidney Stones
Liver Detoxification
Memory and Brain Function
Menopause
Menorrhagia
Menstrual Irregularity
Menstruation (scant)
Mental Illness
Migraine
Mood Swings
Morning Sickness
Nausea and Vomiting
Nerve Damage
Nervous Exhaustion
Nervousness
Neuralgia and Neuritis
Nightmares
Numbness
Obsessive Compulsive Disorder
PMS (general)
PMS Type A
PMS Type C
PMS Type D
PMS Type H
PMS Type P
PMS Type S
Post Partum Weakness
Pregnancy (herbs and supplements for)
Progesterone (low)
Rheumatoid Arthritis
Schizophrenia
Seborrhea
Seizures
Sleep (restless and disturbed)
Sore or Geographic Tongue
Stress
Thinking (cloudy)
Tics
TMJ
Tuberculosis
Twitching
Worry

Products containing vitamin B6

Health Concerns

Brands

Evidence supporting the use of: Vitamin B6
For the health condition: Arthritis

Table of Contents

Synopsis

Other ingredients used for Arthritis

Other health conditions supported by vitamin B6

Products containing vitamin B6

Health Concerns

Brands

Evidence supporting the use of: Vitamin B6For the health condition: Arthritis

Table of Contents

Synopsis

Other ingredients used for Arthritis

Other health conditions supported by vitamin B6

Products containing vitamin B6

Evidence supporting the use of: Vitamin B6
For the health condition: Arthritis