Relationship: Brain and riboflavin (vitamin B2)

Evidence supporting the use of: Riboflavin (vitamin B2)
For the body system: Brain

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Riboflavin (vitamin B2) is a water-soluble vitamin essential for human health. It plays a key role in energy metabolism as a component of the coenzymes flavin mononucleotide (FMN) and flavin adenine dinucleotide (FAD), which are necessary for the function of various enzymes involved in the production of cellular energy. In the context of the brain and nervous system, riboflavin supports mitochondrial function, which is critical for neuronal health and neurotransmitter synthesis.

There is scientific evidence supporting riboflavin’s role in neurological health, primarily in the context of deficiency. Riboflavin deficiency can lead to neurological symptoms such as fatigue, cognitive impairment, and, in severe cases, neuropathy. Furthermore, riboflavin supplementation has demonstrated efficacy in certain neurological conditions; for example, several clinical studies have shown that riboflavin supplementation (typically 400 mg/day) can reduce the frequency and severity of migraine headaches, likely due to its role in mitochondrial energy production in neuronal cells. However, evidence supporting benefits for broader brain health or cognitive enhancement in well-nourished individuals is limited.

In summary, riboflavin is scientifically validated as essential for normal brain and nervous system function due to its metabolic roles, and there is moderate evidence supporting its use in specific neurological conditions like migraines. However, its routine use for enhancing overall brain function in the general population is not strongly supported by current evidence.

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Other body systems supported by riboflavin (vitamin B2)

Blood
Brain
Digestive System
Eyes
Gastrointestinal Tract
Glandular System
Hair
Hepatic System
Immune System
Intestinal System
Liver
Mitochondria
Mucus Membranes
Skin

Products containing riboflavin (vitamin B2)

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Evidence supporting the use of: Riboflavin (vitamin B2)
For the body system: Brain

Table of Contents

Synopsis

Other ingredients that support Brain

Other body systems supported by riboflavin (vitamin B2)

Products containing riboflavin (vitamin B2)

Health Concerns

Brands

Evidence supporting the use of: Riboflavin (vitamin B2)For the body system: Brain

Table of Contents

Synopsis

Other ingredients that support Brain

Other body systems supported by riboflavin (vitamin B2)

Products containing riboflavin (vitamin B2)

Evidence supporting the use of: Riboflavin (vitamin B2)
For the body system: Brain